The corticostriatal pathway is believed to utilize the excitatory amino acid glutamate as its
transmitter, and the striatum contains high levels of all glutamate receptor subtypes. It has …

The role of D1 dopamine (DA) receptors in mediating the ability of DA to modulate
responses attributable to activation of NMDA receptors was examined in mice lacking D1A …

The basal ganglia comprise a subcortical brain system through which the cerebral cortex
affects behavior. The principal input structure is the striatum, whose GABAergic medium …

Human fetal mesencephalic dopamine (DA) neurons, obtained from 6.5–9 week old aborted
fetuses, were grafted to the striatum of immunosuppressed rats with 6-hydroxydopamine …

Cannabinoid modulation of dopaminergic transmission is suggested by the ability of delta9-
tetrahydrocanabinoid to affect motor and motivated behaviors in a manner similar to that …

An antibody to glutamate decarboxylase has been used in a light and electron microscopic
study of the neostriatum of rats that had received intracerebral injections of colchicine. In the …

Prepulse inhibition (PPI) is the normal reduction in startle reflex that occurs when a startling
stimulus is preceded by a weak prepulse. PPI is reduced in patients with schizophrenia and …

In the present study the effect of L-glutamic acid (L-Glu), N-methyl-D-aspartic acid (NMDA),
kainic acid (KA) and quisqualic acid (QUIS) on the release of endogenous dopamine (DA) …

Units of dendritic branches called dendritic spines represent more than simply decorative
appendages of the neuron and actively participate in integrative functions of “spinous” nerve …

2.2. Heterogeneity of the dopaminergic and cholinergic systems in the striatum 756 3.
MULTIPLICITY, DISTRIBUTION AND SIGNAL TRANSDUCTION ASPECTS OF DOPAMINE …