Naringenin ameliorates learning and memory impairment following systemic lipopolysaccharide challenge in the rat
MR Khajevand-Khazaei, P Ziaee… - European Journal of …, 2018 - Elsevier
Systemic inflammation following infection is usually associated with long-term complications
including cognitive deficit and dementia. Neuroinflammation and cognitive decline are also …
including cognitive deficit and dementia. Neuroinflammation and cognitive decline are also …
Recent progress in the pharmacotherapy of Alzheimer's disease
R Khoury, K Patel, J Gold, S Hinds, GT Grossberg - Drugs & aging, 2017 - Springer
Alzheimer's disease is the most common major neurocognitive disorder with substantial
social and economic impacts. This article is an update on current pharmacotherapy …
social and economic impacts. This article is an update on current pharmacotherapy …
Sulfur-containing therapeutics in the treatment of Alzheimer's disease
Sulfur is widely existent in natural products and synthetic organic compounds as
organosulfur, which are often associated with a multitude of biological activities …
organosulfur, which are often associated with a multitude of biological activities …
[HTML][HTML] β-Ecdysterone protects SH-SY5Y cells against β-amyloid-induced apoptosis via c-Jun N-terminal kinase-and Akt-associated complementary pathways
T Xu, C Niu, X Zhang, M Dong - Laboratory investigation, 2018 - Elsevier
Recently, the significantly higher incidence of Alzheimer's disease (AD) in women than in
men has been attributed to the loss of neuroprotective estrogen after menopause. Does …
men has been attributed to the loss of neuroprotective estrogen after menopause. Does …
EKGDR: An End-to-End Knowledge Graph-Based Method for Computational Drug Repurposing
J Tayebi, B BabaAli - Journal of Chemical Information and …, 2024 - ACS Publications
The lengthy and expensive process of developing new drugs from scratch, coupled with a
high failure rate, has prompted the emergence of drug repurposing/repositioning as a more …
high failure rate, has prompted the emergence of drug repurposing/repositioning as a more …
The efficacy of donepezil administration on acetylcholinesterase activity and altered redox homeostasis in Alzheimer's disease
Alzheimer's disease (AD) is a serious multifactorial disorder with progressive
neurodegenerative outcomes related with impaired redox homeostasis. Inhibition of the …
neurodegenerative outcomes related with impaired redox homeostasis. Inhibition of the …
Neuroprotective effects of riluzole in Alzheimer's disease: A comprehensive review
M Golmohammadi, M Mahmoudian… - Fundamental & …, 2024 - Wiley Online Library
Background Despite several hundred clinical trials of drugs that initially showed promise,
there has been limited clinical improvement in Alzheimer's disease (AD). This may be …
there has been limited clinical improvement in Alzheimer's disease (AD). This may be …
Pharmacological interventions to attenuate Alzheimer's disease progression: The story so far
FH Bazzari, DM Abdallah… - Current Alzheimer …, 2019 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease and the most
common cause of dementia in the elderly. Up to date, the available pharmacological options …
common cause of dementia in the elderly. Up to date, the available pharmacological options …
Synthesis, characterization, in-silico, and pharmacological evaluation of new 2-amino-6‑trifluoromethoxy benzothiazole derivatives
S Malik, GA Miana, A Ata, M Kanwal, S Maqsood… - Bioorganic …, 2023 - Elsevier
Abstract Alzheimer's disease (AD), a relentless neurodegenerative disorder, is still waiting
for safer profile drugs, risk factors affecting AD's pathogenesis include aβ accumulation, tau …
for safer profile drugs, risk factors affecting AD's pathogenesis include aβ accumulation, tau …
Scutellarin alleviates lipopolysaccharide-induced cognitive deficits in the rat: Insights into underlying mechanisms
Inflammation is a common hallmark of neurodegenerative disorders. Systemic inflammation
is usually associated with cognitive deficits. Scutellarin is a flavone with established …
is usually associated with cognitive deficits. Scutellarin is a flavone with established …