Relationship between thyroid hormones and central nervous system metabolism in physiological and pathological conditions

N Sawicka-Gutaj, N Zawalna, P Gut… - Pharmacological Reports, 2022 - Springer
Thyroid hormones (THs) play an important role in the regulation of energy metabolism. They
also take part in processes associated with the central nervous system (CNS), including …

[HTML][HTML] Sex differences in frailty among older adults

RS Zeidan, T McElroy, L Rathor, MS Martenson… - Experimental …, 2023 - Elsevier
By definition, aging is a natural, gradual and continuous process. On the other hand, frailty
reflects the increase in vulnerability to stressors and shortens the time without disease …

[HTML][HTML] Genetic underpinning of the comorbidity between type 2 diabetes and osteoarthritis

AL Arruda, A Hartley, G Katsoula, GD Smith… - The American Journal of …, 2023 - cell.com
Multimorbidity is a rising public health challenge with important implications for health
management and policy. The most common multimorbidity pattern is the combination of …

The effect of hyperthyroidism on cognitive function, neuroinflammation, and necroptosis in APP/PS1 mice

K Lou, S Liu, F Zhang, W Sun, X Su, W Bi, Q Yin… - Journal of Translational …, 2023 - Springer
Background Increasing evidence has linked the thyroid dysfunction to the pathogenesis of
dementia. Evidence from clinical studies has demonstrated that hypothyroidism is related to …

Insight into potential interactions of thyroid hormones, sex hormones and their stimulating hormones in the development of non-alcoholic fatty liver disease

E Fröhlich, R Wahl - Metabolites, 2022 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is a common manifestation of metabolic
syndrome. In addition to lifestyle, endocrine hormones play a role in the dysregulation of …

[HTML][HTML] Environmental exposure to perchlorate, nitrate and thiocyanate, and thyroid function in Chinese adults: a community-based cross-sectional study

L King, Q Wang, L Xia, P Wang, G Jiang, W Li… - Environment …, 2023 - Elsevier
Background Evidence on environmental exposure to perchlorate, nitrate, and thiocyanate,
three thyroidal sodium iodine symporter (NIS) inhibitors, and thyroid function in the Chinese …

Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging

A Sola-García, MÁ Cáliz-Molina, I Espadas… - Communications …, 2023 - nature.com
ATP-citrate lyase is a central integrator of cellular metabolism in the interface of protein,
carbohydrate, and lipid metabolism. The physiological consequences as well as the …

[HTML][HTML] Associations of urinary perchlorate, nitrate and thiocyanate with central sensitivity to thyroid hormones: A US population-based cross-sectional study

L King, Y Huang, T Li, Q Wang, W Li, Z Shan… - Environment …, 2022 - Elsevier
Background Perchlorate, nitrate, and thiocyanate are three well-known sodium iodine
symporter inhibitors, however, associations of their individual and concurrent exposure with …

Thermogenic adipose tissue aging: Mechanisms and implications

GN Silva, AA Amato - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Adipose tissue undergoes significant anatomical and functional changes with aging, leading
to an increased risk of metabolic diseases. Age-related changes in adipose tissue include …

Thyroid hormone changes correlate to combined breast cancer with primary thyroid cancer

J Jin, J Li, Y Liu, Q Shi, B Zhang, Y Ji… - Breast Cancer: Targets …, 2024 - Taylor & Francis
Background Breast cancer and thyroid cancer are two prevalent malignancies in women,
and a potential association between the two diseases has been suggested. Methods This …