[HTML][HTML] Effects of perioperative use of esketamine on postpartum depression risk in patients undergoing cesarean section: a randomized controlled trial
QR Liu, QK Zong, LL Ding, HY Dai, Y Sun… - Journal of affective …, 2023 - Elsevier
Background Postpartum depression (PPD) is a prevalent public health issue. Although
ketamine has prophylactic effects on PPD in women undergoing cesarean section, the …
ketamine has prophylactic effects on PPD in women undergoing cesarean section, the …
[HTML][HTML] A role of splenic heme biosynthesis pathway in the persistent prophylactic actions of arketamine in lipopolysaccharide-treated mice
L Ma, L Wang, Y Qu, X Wan, K Hashimoto - Translational Psychiatry, 2023 - nature.com
Relapse is common in remitted patients with major depressive disorder (MDD). Arketamine,
an (R)-enantiomer of ketamine, has persistent prophylactic actions in an inflammatory model …
an (R)-enantiomer of ketamine, has persistent prophylactic actions in an inflammatory model …
[HTML][HTML] From helplessness to controllability: toward a neuroscience of resilience
“Learned helplessness” refers to debilitating outcomes, such as passivity and increased
fear, that follow an uncontrollable adverse event, but do not when that event is controllable …
fear, that follow an uncontrollable adverse event, but do not when that event is controllable …
Prophylactic effects of arketamine, but not hallucinogenic psychedelic DOI nor non-hallucinogenic psychedelic analog lisuride, in lipopolysaccharide-treated mice and …
G Liu, L Ma, Y Qu, X Wan, D Xu, M Zhao… - Pharmacology …, 2023 - Elsevier
Anesthetic ketamine and classical psychedelics that act as 5-hydroxytryptamine-2A receptor
(5-HT 2A R) agonists demonstrated rapid and sustained antidepressant actions in patients …
(5-HT 2A R) agonists demonstrated rapid and sustained antidepressant actions in patients …
Investigating resistance to antidepressants in animal models
JE Peña, BF Corbett, CA Tamminga, S Bhatnagar… - Neuroscience, 2024 - Elsevier
Major depressive disorder is one of the most prevalent psychiatric diseases, and up to 30-
40% of patients remain symptomatic despite treatment. Novel therapies are sorely needed …
40% of patients remain symptomatic despite treatment. Novel therapies are sorely needed …
A role of gut–brain axis on prophylactic actions of arketamine in male mice exposed to chronic restrain stress
L Ma, A Eguchi, G Liu, Y Qu, X Wan… - Pharmacology …, 2024 - Elsevier
The gut–brain axis, which includes gut microbiota and microbiome-derived metabolites,
might be implicated in depression. We reported the sustained prophylactic effects of a new …
might be implicated in depression. We reported the sustained prophylactic effects of a new …
(R, S)-ketamine's rapid-acting antidepressant effects are modulated by NR2B-containing NMDA receptors on adult-born hippocampal neurons
Standard antidepressant treatments often take weeks to reach efficacy and are ineffective for
many patients.(R, S)-ketamine, an N-methyl-D-aspartate (NMDA) antagonist, has been …
many patients.(R, S)-ketamine, an N-methyl-D-aspartate (NMDA) antagonist, has been …
Efficacy of Ketamine for Depression and Other Mental Health Conditions: Top 10 Studies of 2023
PD January - psychedelicspotlight.com
The results suggest that ketamine could represent a more favorable option for TRD,
potentially leading to a paradigm shift in treatment methodologies due to its higher patient …
potentially leading to a paradigm shift in treatment methodologies due to its higher patient …
[引用][C] Ketamine and its metabolites: Potential as novel treatments for depression
K Hashimoto, S Chaki - Neuropharmacology, 2023 - pubmed.ncbi.nlm.nih.gov
Ketamine and its metabolites: Potential as novel treatments for depression Ketamine and its
metabolites: Potential as novel treatments for depression Neuropharmacology. 2023 Jun 1:230:109492 …
metabolites: Potential as novel treatments for depression Neuropharmacology. 2023 Jun 1:230:109492 …