Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
[HTML][HTML] Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections
Y Wu, D Battalapalli, MJ Hakeem, V Selamneni… - Journal of …, 2021 - Springer
Antibiotic resistance is spreading rapidly around the world and seriously impeding efforts to
control microbial infections. Although nucleic acid testing is widely deployed for the …
control microbial infections. Although nucleic acid testing is widely deployed for the …
[HTML][HTML] Novel strategy to combat antibiotic resistance: a sight into the combination of CRISPR/Cas9 and nanoparticles
Antibiotic resistance is a significant crisis that threatens human health and safety worldwide.
There is an urgent need for new strategies to control multidrug-resistant (MDR) bacterial …
There is an urgent need for new strategies to control multidrug-resistant (MDR) bacterial …
DNA in nanochannels: theory and applications
Nanofluidic structures have over the last two decades emerged as a powerful platform for
detailed analysis of DNA on the kilobase pair length scale. When DNA is confined to a …
detailed analysis of DNA on the kilobase pair length scale. When DNA is confined to a …
Polymer brushes on silica nanostructures prepared by aminopropylsilatrane click chemistry: superior antifouling and biofunctionality
J Andersson, J Järlebark, S Kk… - … Applied Materials & …, 2023 - ACS Publications
In nanobiotechnology, the importance of controlling interactions between biological
molecules and surfaces is paramount. In recent years, many devices based on …
molecules and surfaces is paramount. In recent years, many devices based on …
Single-molecule analysis of nucleic acid biomarkers–A review
Nucleic acids are important biomarkers for disease detection, monitoring, and treatment.
Advances in technologies for nucleic acid analysis have enabled discovery and clinical …
Advances in technologies for nucleic acid analysis have enabled discovery and clinical …
Experimental approaches to tracking mobile genetic elements in microbial communities
Horizontal gene transfer is an important mechanism of microbial evolution and is often
driven by the movement of mobile genetic elements between cells. Due to the fact that …
driven by the movement of mobile genetic elements between cells. Due to the fact that …
[HTML][HTML] Strain-level bacterial typing directly from patient samples using optical DNA mapping
M Nyblom, A Johnning, K Frykholm, M Wrande… - Communications …, 2023 - nature.com
Background Identification of pathogens is crucial to efficiently treat and prevent bacterial
infections. However, existing diagnostic techniques are slow or have a too low resolution for …
infections. However, existing diagnostic techniques are slow or have a too low resolution for …
Optical maps of plasmids as a proxy for clonal spread of MDR bacteria: a case study of an outbreak in a rural Ethiopian hospital
Objectives MDR bacteria have become a prevailing health threat worldwide. We here aimed
to use optical DNA mapping (ODM) as a rapid method to trace nosocomial spread of …
to use optical DNA mapping (ODM) as a rapid method to trace nosocomial spread of …
[HTML][HTML] A simple cut and stretch assay to detect antimicrobial resistance genes on bacterial plasmids by single-molecule fluorescence microscopy
Antimicrobial resistance (AMR) is a fast-growing threat to global health. The genes
conferring AMR to bacteria are often located on plasmids, circular extrachromosomal DNA …
conferring AMR to bacteria are often located on plasmids, circular extrachromosomal DNA …