[PDF][PDF] What is a cell type and how to define it?

H Zeng - Cell, 2022 - cell.com
Cell types are the basic functional units of an organism. Cell types exhibit diverse
phenotypic properties at multiple levels, making them challenging to define, categorize, and …

Neuron tracing from light microscopy images: automation, deep learning and bench testing

Y Liu, G Wang, GA Ascoli, J Zhou, L Liu - Bioinformatics, 2022 - academic.oup.com
Motivation Large-scale neuronal morphologies are essential to neuronal typing, connectivity
characterization and brain modeling. It is widely accepted that automation is critical to the …

Multimodal mapping of cell types and projections in the central nucleus of the amygdala

Y Wang, S Krabbe, M Eddison, FE Henry, G Fleishman… - Elife, 2023 - elifesciences.org
The central nucleus of the amygdala (CEA) is a brain region that integrates external and
internal sensory information and executes innate and adaptive behaviors through distinct …

[HTML][HTML] Probing neural circuit mechanisms in Alzheimer's disease using novel technologies

SF Grieco, TC Holmes, X Xu - Molecular Psychiatry, 2023 - nature.com
The study of Alzheimer's Disease (AD) has traditionally focused on neuropathological
mechanisms that has guided therapies that attenuate neuropathological features. A new …

[PDF][PDF] Activation of VIP interneurons in the prefrontal cortex ameliorates neuropathic pain aversiveness

M Li, H Zhou, S Teng, G Yang - Cell reports, 2022 - cell.com
While dysfunction of the medial prefrontal cortex (mPFC) has been implicated in chronic
pain, the underlying neural circuits and the contribution of specific cellular populations …

Single-neuron analysis of dendrites and axons reveals the network organization in mouse prefrontal cortex

L Gao, S Liu, Y Wang, Q Wu, L Gou, J Yan - Nature Neuroscience, 2023 - nature.com
Single-neuron analysis of dendrites and axons reveals the network organization in mouse
prefrontal cortex | Nature Neuroscience Skip to main content Thank you for visiting nature.com …

Resolving the prefrontal mechanisms of adaptive cognitive behaviors: A cross-species perspective

IL Hanganu-Opatz, T Klausberger, T Sigurdsson… - Neuron, 2023 - cell.com
The prefrontal cortex (PFC) enables a staggering variety of complex behaviors, such as
planning actions, solving problems, and adapting to new situations according to external …

[HTML][HTML] Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus

K Tossell, X Yu, P Giannos, B Anuncibay Soto… - Nature …, 2023 - nature.com
The prefrontal cortex (PFC) enables mammals to respond to situations, including internal
states, with appropriate actions. One such internal state could be 'tiredness'. Here, using …

[HTML][HTML] A guide to the BRAIN Initiative Cell Census Network data ecosystem

M Hawrylycz, ME Martone, GA Ascoli, JG Bjaalie… - PLoS …, 2023 - journals.plos.org
Characterizing cellular diversity at different levels of biological organization and across data
modalities is a prerequisite to understanding the function of cell types in the brain …

Insulin-like growth factor 1 regulates excitatory synaptic transmission in pyramidal neurons from adult prefrontal cortex

S Yue, Y Wang, ZJ Wang - Neuropharmacology, 2022 - Elsevier
Insulin-like growth factor 1 (IGF1) influences synaptic function in addition to its role in brain
development and aging. Although the expression levels of IGF1 and IGF1 receptor (IGF1R) …