Preparation, characterization, and biological evaluation of a hydrophilic peptide loaded on PEG-PLGA nanoparticles

L Marinelli, M Ciulla, JAS Ritsema, CF van Nostrum… - Pharmaceutics, 2022 - mdpi.com
The encapsulation of peptides and proteins in nanosystems has been extensively
investigated for masking unfavorable biopharmaceutical properties, including short half-life …

Aptamers-based Strategies for the Treatment of Microbial Infections

A Di Rienzo, L Marinelli, A Di Stefano… - Letters in Drug …, 2024 - ingentaconnect.com
Background: Nowadays, infectious diseases caused by bacteria are one of the major risks
for the human population worldwide. Antimicrobial resistance determined the necessity to …

[HTML][HTML] Assessment of therapeutic bio-activity of cinnamoyl sulfonamide hydroxamate in squamous cell carcinoma

E Cherian, M Goyal, N Mittal, V Yesodharan… - Cureus, 2023 - ncbi.nlm.nih.gov
Background Cancer is the second most common cause of death. Oral squamous cell
carcinoma (OSCC) represents the most frequent of all oral neoplasms. Many treatment …

Anti-hyperglycemic contours of Madhugrit are robustly translated in the Caenorhabditis elegans model of lipid accumulation by regulating oxidative stress and …

A Balkrishna, V Gohel, N Pathak, M Tomer… - Frontiers in …, 2022 - frontiersin.org
Background The prevalence of diabetes has considerably increased in recent years. In the
long run, use of dual therapy of anti-diabetic agents becomes mandatory to attain …

Anti-obesity and anti-inflammatory effects of novel carvacrol derivatives on 3T3-L1 and WJ-MSCs cells

I Cacciatore, S Spalletta, A Di Rienzo, V Flati… - Pharmaceuticals, 2023 - mdpi.com
(1) Background: Obesity, a complex metabolic disease resulting from an imbalance between
food consumption and energy expenditure, leads to an increase in adipocytes and chronic …

Sustainable Management of Genotoxic Aromatic Pollutants: Role of Microbial Traits in Efficient Bioremediation and Resource Recovery

B Mohapatra, PS Phale - Current Pollution Reports, 2022 - Springer
Abstract Purpose of Review Despite genetic, metabolic, and enzymatic studies of xenobiotic-
degrading microbe (s), bioremediation has remained inefficient at the field level. The …

Development of Biocompatible Ciprofloxacin–Gold Nanoparticle Coated Sutures for Surgical Site Infections

S Sampathi, PK Tiriya, S Dodoala, V Junnuthula… - Pharmaceutics, 2022 - mdpi.com
Surgical site infections (SSIs) are mainly observed after surgeries that use biomaterials. The
aim of this present work was to develop ciprofloxacin hydrochloride (CPH)-loaded gold …

Exploring the therapeutic potential of cinnamoyl derivatives in attenuating inflammation in lipopolysaccharide-induced Caco-2 cells

M Reale, E Costantini, L Aielli, AD Rienzo… - Future Medicinal …, 2024 - Taylor & Francis
Aim: In gastrointestinal (GI) diseases, lipopolysaccharide (LPS) exacerbates gut-barrier
dysfunction and inflammation. Cinnamoyl derivatives show potential in mitigating LPS …

Bioassay-guided isolation and identification of antibacterial compounds from Piper betle leaf with inhibitory activity against the Vibrio species in shrimp

AK Ghosh, SK Panda, H Hu, L Schoofs… - Journal of Essential Oil …, 2024 - Taylor & Francis
The present study examined the antimicrobial effects of betel leaf (Piper betle) extracts
against Vibrio spp. along with the isolation of the most prevalent bioactive components using …

Special Issue “Drug Candidates for the Treatment of Infectious Diseases”

C Man Chin, JL Dos Santos - Pharmaceuticals, 2023 - mdpi.com
Infectious diseases encompass a range of conditions stemming from parasites [1, 2],
bacteria [3], viruses [4], fungi [5], or other parasitic organisms that negatively affect millions of …