[HTML][HTML] Exosome-derived circCCAR1 promotes CD8+ T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma

Z Hu, G Chen, Y Zhao, H Gao, L Li, Y Yin, J Jiang… - Molecular Cancer, 2023 - Springer
Abstract Background Circular RNAs (circRNAs) can be encapsulated into exosomes to
participate in intercellular communication, affecting the malignant progression of a variety of …

[HTML][HTML] Roles of Extracellular Vesicles on the Progression and Metastasis of Hepatocellular Carcinoma

TW Seay, Z Suo - Cells, 2023 - mdpi.com
Liver cancer is a global health challenge as it is the third leading cause of cancer death
worldwide. Hepatocellular carcinoma (HCC) is the most common type of liver cancer and is …

[HTML][HTML] Mechanism underlying circRNA dysregulation in the TME of digestive system cancer

Z Wu, X Yu, S Zhang, Y He, W Guo - Frontiers in Immunology, 2022 - frontiersin.org
Circular RNAs (circRNAs) are a new series of noncoding RNAs (ncRNAs) that have been
reported to be expressed in eukaryotic cells and have a variety of biological functions in the …

[HTML][HTML] Dynamic changes in the transcriptome of tRNA-derived small RNAs related with fat metabolism

T Liao, M Gan, Y Lei, Y Wang, L Chen, L Shen, L Zhu - Scientific Data, 2023 - nature.com
The prevalence of obesity and overweight is steadily rising, posing a significant global
challenge for humanity. The fundamental cause of obesity and overweight lies in the …

[HTML][HTML] Advances in research of biological functions of Isthmin-1

L Menghuan, Y Yang, M Qianhe, Z Na… - Journal of Cell …, 2023 - Springer
Abstract Isthmin-1 (ISM1) was initially thought to be a brain secretory factor, but with the
development of technical means of research and the refinement of animal models …

Nucleus‐localized circSLC39A5 suppresses hepatocellular carcinoma development by binding to STAT1 to regulate TDG transcription

M Liu, M Lai, D Li, R Zhang, L Wang, W Peng… - Cancer …, 2023 - Wiley Online Library
Accumulating evidence indicates that circular RNAs (circRNAs) are inextricably linked to
cancer development. However, the function and mechanism of nucleus‐localized circRNAs …

[HTML][HTML] High expression of Ezh2 mediated by ncrnas correlates with poor prognosis and tumor immune infiltration of hepatocellular carcinoma

Z Chen, X Lin, Z Wan, M Xiao, C Ding, P Wan, Q Li… - Genes, 2022 - mdpi.com
Background: Hepatocellular carcinoma (HCC) is the predominant form of liver cancer and is
accompanied by a complex regulatory network. Increasing evidence suggests that an …

[HTML][HTML] Emerging roles of interactions between ncRNAs and other epigenetic modifications in breast cancer

J Xie, L Gan, B Xue, X Wang, X Pei - Frontiers in Oncology, 2023 - ncbi.nlm.nih.gov
Up till the present moment, breast cancer is still the leading cause of cancer-related death in
women worldwide. Although the treatment methods and protocols for breast cancer are …

[HTML][HTML] Oncogenic roles of LINC01234 in various forms of human cancer

M Kong, X Yu, Q Zheng, S Zhang, W Guo - Biomedicine & …, 2022 - Elsevier
Abnormal expression of long non-coding RNAs (lncRNAs) plays an essential role in various
malignant neoplasia. As a newly identified lncRNA, LINC01234 is abnormally expressed in …

[HTML][HTML] Network regulatory mechanism of ncRNA on the Wnt signaling pathway in osteoporosis

F An, X Meng, L Yuan, Y Niu, J Deng, Z Li, Y Liu, R Xia… - Cell Division, 2023 - Springer
Non-coding RNA (ncRNA) is a type of non-protein-coding RNA molecule transcribed from
the genome which performs broad regulation of a variety of biological functions in human …