Prospects and challenges of electrospun cell and drug delivery vehicles to correct urethral stricture

S Farzamfar, E Elia, S Chabaud, M Naji… - International Journal of …, 2022 - mdpi.com
Current therapeutic modalities to treat urethral strictures are associated with several
challenges and shortcomings. Therefore, significant strides have been made to develop …

Current state of urethral tissue engineering

N Mangir, KJ Wilson, NI Osman… - Current opinion in …, 2019 - journals.lww.com
The research with tissue engineering of the urethra has not yet been translated into a
clinically available material. This is an area where much more research is needed and we …

[HTML][HTML] Recent Advances in treatment of urethral stricture disease in men

N Mangir, C Chapple - F1000Research, 2020 - ncbi.nlm.nih.gov
Urethral stricturing is a narrowing of the urethral lumen as a result of ischaemic
spongiofibrosis. The main challenge of currently available treatment options is recurrence of …

[HTML][HTML] Enhanced expression of hyaluronic acid in osteoarthritis-affected knee-cartilage chondrocytes during three-dimensional in vitro culture in a hyaluronic-acid …

S Katoh, H Yoshioka, R Senthilkumar, S Preethy… - The Knee, 2021 - Elsevier
Background Chondrocyte transplantation to address cartilage damage is an established
solution. Because hyaluronic acid (HA) is an essential component for homeostasis of the …

Cell-based therapy for urethral regeneration: a narrative review and future perspectives

Y Jin, W Zhao, M Yang, W Fang, G Gao, Y Wang, Q Fu - biomedicines, 2023 - mdpi.com
Urethral stricture is a common urological disease that seriously affects quality of life.
Urethroplasty with grafts is the primary treatment, but the autografts used in clinical practice …

Reversal of senescence-associated beta-galactosidase expression during in vitro three-dimensional tissue-engineering of human chondrocytes in a polymer scaffold

S Katoh, A Fujimaru, M Iwasaki, H Yoshioka… - Scientific Reports, 2021 - nature.com
Regenerative medicine applications require cells that are not inflicted with senescence after
in vitro culture for an optimal in vivo outcome. Methods to overcome replicative senescence …

Engraftment of transplanted buccal epithelial cells onto the urethrotomy site, proven immunohistochemically in rabbit model; a feat to prevent urethral stricture …

A Horiguchi, M Shinchi, K Ojima, Y Hirano… - Stem Cell Reviews and …, 2023 - Springer
Urethral strictures characterized by narrowing of the urethral lumen is a common disorder in
men caused by inflammation, infection or trauma. Less invasive transurethral procedures in …

Successful engraftment of epithelial cells derived from autologous rabbit buccal mucosal tissue, encapsulated in a polymer scaffold in a rabbit model of a urethral …

A Horiguchi, K Ojima, M Shinchi, T Kushibiki… - Regenerative …, 2021 - Elsevier
Background A pilot study reported an autologous buccal mucosal cell transplant in humans
through the trans-urethral route using the buccal epithelium expanded and encapsulated in …

Advancements in transurethral management of urethral stricture disease

M Hughes, S Blakely, D Nikolavsky - Current Opinion in Urology, 2021 - journals.lww.com
Advancements in transurethral management of urethral strictu... : Current Opinion in Urology
Advancements in transurethral management of urethral stricture disease : Current Opinion in …

Recent trends and advances in anterior urethroplasty

E Naud, K Rourke - Urologic Clinics, 2022 - urologic.theclinics.com
Urethral stricture is likely the oldest urologic disease with documentation of its existence
more than 4000 years ago. 1 At its simplest,“urethral stricture” refers to any abnormal …