[HTML][HTML] Long Noncoding RNA HCP5, a Hybrid HLA Class I Endogenous Retroviral Gene: Structure, Expression, and Disease Associations

JK Kulski - Cells, 2019 - mdpi.com
The HCP5 RNA gene (NCBI ID: 10866) is located centromeric of the HLA-B gene and
between the MICA and MICB genes within the major histocompatibility complex (MHC) class …

[HTML][HTML] Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription

Q Chen, H Wang, Z Li, F Li, L Liang, Y Zou, H Shen… - Journal of …, 2022 - Elsevier
Background & Aims Intrahepatic cholangiocarcinoma (ICC) is a primary liver cancer with
high aggressiveness and extremely poor prognosis. The role of circular RNAs (circRNAs) in …

[HTML][HTML] Functions and mechanisms of miR-186 in human cancer

Z Wang, HH Sha, HJ Li - Biomedicine & Pharmacotherapy, 2019 - Elsevier
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the post-
transcriptional level. Mounting evidence suggests the involvement of miRNAs in …

[HTML][HTML] MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p/AMPK/PGC1α/CEBPB axis to promote stemness and chemo-resistance of gastric …

H Wu, B Liu, Z Chen, G Li, Z Zhang - Cell death & disease, 2020 - nature.com
Chemotherapy is the first-tier treatment regime for gastric cancer (GC) patients at advance
stages. Mesenchymal stem cell (MSC) cam affect drug-resistance of GC cells in tumor …

[HTML][HTML] Integration of scRNA-Seq and bulk RNA-Seq to analyse the heterogeneity of ovarian cancer immune cells and establish a molecular risk model

L Liang, J Yu, J Li, N Li, J Liu, L Xiu, J Zeng… - Frontiers in …, 2021 - frontiersin.org
Background Considerable evidence suggests that the heterogeneity of ovarian cancer (OC)
is a major cause of treatment failure. Single-cell RNA sequencing (scRNA-seq) is a powerful …

[HTML][HTML] ALKBH5-mediated m6A modification of circCCDC134 facilitates cervical cancer metastasis by enhancing HIF1A transcription

L Liang, Y Zhu, J Li, J Zeng, L Wu - Journal of Experimental & Clinical …, 2022 - Springer
Background Metastasis is the main cause of mortality in cervical cancer (CC). Circular RNAs
(circRNAs) have been demonstrated to play a crucial role in carcinoma biology. However …

High-throughput analysis reveals miRNA upregulating α-2, 6-sialic acid through direct miRNA–mRNA interactions

F Jame-Chenarboo, HH Ng, D Macdonald… - ACS Central …, 2022 - ACS Publications
Chemical biology has revealed the importance of sialic acids as a major signal in physiology
and disease. The terminal modification α-2, 6-sialic acid is controlled by the enzymes …

Characterizing miRNA–lncRNA interplay

D Karagkouni, A Karavangeli… - Long Non-Coding RNAs …, 2021 - Springer
Long noncoding RNAs (lncRNAs) are noncoding transcripts, usually longer than 200 nt, that
constitute one of the largest and significantly heterogeneous RNA families. The annotation …

LncRNA HCP5 promotes triple negative breast cancer progression as a ceRNA to regulate BIRC3 by sponging miR‐219a‐5p

L Wang, T Luan, S Zhou, J Lin, Y Yang, W Liu… - Cancer …, 2019 - Wiley Online Library
Emerging evidence has suggested that long noncoding RNAs (lncRNA) involved in the
development and progression of cancer. Triple negative breast cancer (TNBC) was an …

[HTML][HTML] HCP5 is a SMAD3-responsive long non-coding RNA that promotes lung adenocarcinoma metastasis via miR-203/SNAI axis

L Jiang, R Wang, LI Fang, X Ge, L Chen, M Zhou… - Theranostics, 2019 - ncbi.nlm.nih.gov
Introduction: Transforming growth factor-beta (TGFβ) signaling plays a vital role in lung
adenocarcinoma (LUAD) progression. However, the involvement of TGFβ-regulated long …