Hepatitis C virus (HCV) induces persistent infection and causes chronic liver disease in most
infected patients. Vigorous HCV-specific CD4+ and CD8+ T cell responses against HCV …

Acute hepatitis C has a high propensity to become chronic, which provides the rationale for
treating patients with acute disease attempting to prevent chronicity. Almost all published …

Introduction Given the pivotal role of T lymphocytes in the immune system, patients with
septic shock may show T cell abnormalities. We have characterised the T cell compartment …

Infection with hepatitis C virus (HCV) is characterised by a disturbingly high propensity to
progress to persistent infection leading to chronic liver disease which, in a proportion of …

Background: Appropriate treatment of acute hepatitis C is still a matter of controversy due to
the lack of large controlled trials. Aim: To assess the effectiveness of interferon as treatment …

Studies of patients with post-transfusion non-A, non-B hepatitis and their implicated donors
were critical to the discovery of hepatitis C virus (HCV) and to the development and …

Abstract Relatively few patients (≤ 20%) with chronic hepatitis C achieve a sustained
virological response after interferon-α monotherapy. Hence, alternative treatment strategies …

Background. Acute hepatitis C has a high chronicity rate which appears to be significantly
reduced by early antiviral treatment. However, it is unclear if all acutely infected patients …

Diagnosing acute hepatitis C is still difficult. The disease is frequently asymptomatic and
there are no specific diagnostic tests. Most frequently, diagnosis is based on anti HCV …

BACKGROUND & AIMS: Case definitions for recent hepatitis C virus (HCV) infection vary
considerably between studies. The aim of this systematic review was to characterize case …