Influenza A viruses cause pandemics when they cross between species and an
antigenically novel virus acquires the ability to infect and transmit between these new hosts …

Ari Helenius launched the field of enveloped virus fusion in endosomes with a seminal
paper in the Journal of Cell Biology in 1980. In the intervening years, a great deal has been …

Host dependency factors that are required for influenza A virus infection may serve as
therapeutic targets as the virus is less likely to bypass them under drug-mediated selection …

There are at least 21 families of enveloped viruses that infect mammals, and many contain
members of high concern for global human health. All enveloped viruses have a dedicated …

More than 80 different adenovirus (AdV) types infect humans through the respiratory, ocular,
or gastrointestinal tracts. They cause acute clinical mani-festations or persist under humoral …

Protein structural changes induced by external perturbations or internal cues can profoundly
influence protein activity and thus modulate cellular physiology. A number of biophysical …

COVID-19 is one of the most impactful pandemics in recorded history. As such, the
identification of inhibitory drugs against its etiological agent, SARS-CoV-2, is of utmost …

Lipid nanoparticles (LNPs) are currently the most promising clinical nucleic acids drug
delivery vehicles. LNPs prevent the degradation of cargo nucleic acids during blood …

Viruses are highly dependent on the host they infect. Their dependence triggers processes
of virus–host co-adaptation, enabling viruses to explore host resources whilst escaping …

The influenza A virus was isolated for the first time in 1931, and the first attempts to develop
a vaccine against the virus began soon afterwards. In addition to causing seasonal …