In order to investigate the pathogenesis of pigment anomaly-associated hereditary deaf
ness, we studied black-eyed white mutant mice, which become severely deaf in early life …

The melanocytes in the mammalian eye have been thought to produce melanin only during
fetal development and in the very young individual. The recent discovery that latanoprost, a …

Whether melanogenesis occurs in adult eyes is still a matter of controversy. It has been
widely held that the pigment epithelial cells are fully melanized at birth, and that the uveal …

Using monoclonal and polyclonal antibodies to intermediate filaments in the cochleas of
normal and mutant mice, we were able to distinguish between different cell types of the stria …

The development of the research on xenobiotics has made it necessary to improve our
knowledge of the action of such compounds on living systems. While the pharmacological or …

Autoradiography is widely used in toxicological and pharmacological studies to determine
biotransformation, distribution and excretion of compounds. The first part of this review …

Autoradiography has made important contributions to the study of cells and tissues in such
diverse fields as basic medical sciences, pharmaceutical research, toxicology, immunology …