Abstract Background Fistulizing anoperineal lesions (FAPLs) are common and severe
complications of Crohn's disease (CD), exposing patients to the risk of anal sphincter …

Fistulizing anoperineal lesions are severe complications of Crohn's disease (CD) that affect
quality of life with a long-term risk of anal sphincter destruction, incontinence, permanent …

Abstract Introduction: Anastomotic leaks (ALs) are serious postoperative complications.
Current experimental studies designed to investigate leaks are based on acute …

BACKGROUND: Perianal Crohn's disease is associated with poor outcomes and high
medical costs. It is notoriously difficult to treat despite therapeutic advancements for luminal …

METHODS Twelve healthy pigs were randomly divided into two groups. Under general
anesthesia, the experimental group underwent rubber band ligation surgery, and the control …

Refractory Crohn's-like enterocutaneous fistula indicates the aggressive manifestation and
lead to poor prognosis of patients. The development of multidisciplinary strategies for fistula …

Complex anal fistulae remain a challenge for the medical sector as conventional treatments
put patients at risk of incontinence. Clinicians and researchers have become interested in …

5) Baghdadi M, Nagao H, Yoshiyama H, Akiba H, Yagita H, Dosaka-Akita H, Jinushi M:
Combined blockade of TIM-3 and TIM-4 augments cancer vaccine efficacy against …