CRISPR/Cas9 genome editing technology in filamentous fungi: progress and perspective

R Song, Q Zhai, L Sun, E Huang, Y Zhang… - Applied microbiology …, 2019 - Springer
Filamentous fungi play an important role in human health and industrial/agricultural
production. With the increasing number of full genomes available for fungal species, the …

Fungal proteases as emerging biocatalysts to meet the current challenges and recent developments in biomedical therapies: an updated review

M Naeem, S Manzoor, MUH Abid, MBK Tareen… - Journal of Fungi, 2022 - mdpi.com
With the increasing world population, demand for industrialization has also increased to
fulfill humans' living standards. Fungi are considered a source of essential constituents to …

Applications of CRISPR/Cas9 in the synthesis of secondary metabolites in filamentous fungi

C Jiang, G Lv, Y Tu, X Cheng, Y Duan… - Frontiers in …, 2021 - frontiersin.org
Filamentous fungi possess the capacity to produce a wide array of secondary metabolites
with diverse biological activities and structures, such as lovastatin and swainsonine. With the …

[HTML][HTML] Effector biology of biotrophic plant fungal pathogens: Current advances and future prospects

R Jaswal, K Kiran, S Rajarammohan, H Dubey… - Microbiological …, 2020 - Elsevier
The interaction of fungal pathogens with their host requires a novel invading mechanism
and the presence of various virulence-associated components responsible for promoting the …

CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis …

T Leisen, F Bietz, J Werner, A Wegner… - PLoS …, 2020 - journals.plos.org
CRISPR/Cas has become the state-of-the-art technology for genetic manipulation in diverse
organisms, enabling targeted genetic changes to be performed with unprecedented …

Versatile applications of the CRISPR/Cas toolkit in plant pathology and disease management

MS Wheatley, Y Yang - Phytopathology®, 2021 - Am Phytopath Society
New tools and advanced technologies have played key roles in facilitating basic research in
plant pathology and practical approaches for disease management and crop health …

CRISPR/Cas9 gene editing: an unexplored frontier for forest pathology

EN Dort, P Tanguay, RC Hamelin - Frontiers in Plant Science, 2020 - frontiersin.org
CRISPR/Cas9 gene editing technology has taken the scientific community by storm since its
development in 2012. First discovered in 1987, CRISPR/Cas systems act as an adaptive …

Progress and challenges: development and implementation of CRISPR/Cas9 technology in filamentous fungi

Q Wang, JJ Coleman - Computational and structural biotechnology journal, 2019 - Elsevier
Widely distributed in various environmental niches, filamentous fungi play an important role
in industry, drug development, and plant/animal health. Manipulation of the genome and the …

CRISPR-Cas for fungal genome editing: a new tool for the management of plant diseases

IV Muñoz, S Sarrocco, L Malfatti, R Baroncelli… - Frontiers in Plant …, 2019 - frontiersin.org
Background Fungal pathogens are the main factors responsible for the most severe
diseases affecting plants, leading to significant reduction in yield and crop quality and …

Developments and opportunities in fungal strain engineering for the production of novel enzymes and enzyme cocktails for plant biomass degradation

RS Kun, ACS Gomes, KS Hildén, SS Cerezo… - Biotechnology …, 2019 - Elsevier
Fungal strain engineering is commonly used in many areas of biotechnology, including the
production of plant biomass degrading enzymes. Its aim varies from the production of …