In the last decade, preclinical investigations of electroacupuncture mechanisms on
persistent tissue injury (inflammatory), nerve injury (neuropathic), cancer, and visceral pain …

Pain, especially chronic pain, has always been a heated point in both basic and clinical
researches since it puts heavy burdens on both individuals and the whole society. A better …

Recent research suggests that exercise can be effective in reducing pain in animals and
humans with neuropathic pain. To investigate mechanisms in which exercise may improve …

Nerve injury–induced changes of gene expression in dorsal root ganglion (DRG) are critical
for neuropathic pain genesis. However, how these changes occur remains elusive. Here we …

Key points• Unaccustomed strenuous exercise that includes lengthening contraction often
causes delayed onset muscle soreness (DOMS), characterised as muscular mechanical …

Unaccustomed strenuous exercise that includes lengthening contraction (LC) often causes
tenderness and movement related pain after some delay (delayed-onset muscle soreness …

Rearranged during transfection (RET), in complex with glial cell line-derived (GDNF) family
receptor alpha (GFRα), is the canonical signaling receptor for GDNF family ligands (GFLs) …

Neuropathic pain caused by nerve damage is a common and severe class of chronic pain.
Disease-modifying clinical therapies are needed as current treatments typically provide only …

Chronic pain is a debilitating syndrome caused by a variety of disorders, and represents a
major clinical problem because of the lack of adequate medication. In chronic pain, massive …

The neuroinflammatory response to peripheral nerve injury is associated with chronic pain
and significant changes in the molecular expression profiles of mRNAs in neurons, glia and …