Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis

WH Robinson, CM Lepus, Q Wang, H Raghu… - Nature Reviews …, 2016 - nature.com
Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis …

Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin

A Hosseinzadeh, SK Kamrava… - Journal of pineal …, 2016 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive erosion of
articular cartilage. As chondrocytes are the only cell type forming the articular cartilage, their …

Periprosthetic joint infection: the incidence, timing, and predisposing factors

L Pulido, E Ghanem, A Joshi, JJ Purtill… - … and Related Research …, 2008 - journals.lww.com
Periprosthetic joint infection is one of the most challenging complications of joint
arthroplasty. We identified current risk factors of periprosthetic joint infection after modern …

[图书][B] Nutrition through the life cycle

JE Brown, JS Isaacs, UB Krinke, E Lechtenberg… - 2017 - family.uoguelph.ca
She is an applied health researcher with an interest in understanding the development and
expression of health behaviours, specifically eating behaviours and substance misuse. Her …

Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis

S Wandel, P Jüni, B Tendal, E Nüesch, PM Villiger… - Bmj, 2010 - bmj.com
Objective To determine the effect of glucosamine, chondroitin, or the two in combination on
joint pain and on radiological progression of disease in osteoarthritis of the hip or knee …

Pathogenesis and management of pain in osteoarthritis

PA Dieppe, LS Lohmander - The Lancet, 2005 - thelancet.com
The term osteoarthritis describes a common, age-related, heterogeneous group of disorders
characterised pathologically by focal areas of loss of articular cartilage in synovial joints …

Body mass index and susceptibility to knee osteoarthritis: a systematic review and meta-analysis

L Jiang, W Tian, Y Wang, J Rong, C Bao, Y Liu, Y Zhao… - Joint bone spine, 2012 - Elsevier
OBJECTIVE: Excess bodyweight, expressed as increased body mass index, is associated
with osteoarthritis risk, especially in weight bearing joints. However, the strength of the …

Stem cell therapy in a caprine model of osteoarthritis

JM Murphy, DJ Fink, EB Hunziker… - Arthritis & Rheumatism …, 2003 - Wiley Online Library
Objective To explore the role that implanted mesenchymal stem cells may play in tissue
repair or regeneration of the injured joint, by delivery of an autologous preparation of stem …

Intra‐articular corticosteroid for knee osteoarthritis

P Jüni, R Hari, AWS Rutjes, R Fischer… - Cochrane Database …, 1996 - cochranelibrary.com
Background Knee osteoarthritis is a leading cause of chronic pain, disability, and decreased
quality of life. Despite the long‐standing use of intra‐articular corticosteroids, there is an …

Does preoperative rehabilitation for patients planning to undergo joint replacement surgery improve outcomes? A systematic review and meta-analysis of randomised …

L Wang, M Lee, Z Zhang, J Moodie, D Cheng… - BMJ open, 2016 - bmjopen.bmj.com
Objectives The clinical impact of preoperative physiotherapy on recovery after joint
replacement remains controversial. This systematic review aimed to assess the clinical …