[PDF][PDF] Syndromic disorders caused by disturbed human imprinting

D Carli, E Riberi, GB Ferrero… - Journal of Clinical …, 2020 - jag.journalagent.com
Imprinting disorders are a group of congenital diseases caused by dysregulation of genomic
imprinting, affecting prenatal and postnatal growth, neurocognitive development …

Analysis of the hypothalamic oxytocin system and oxytocin receptor‐expressing astrocytes in a mouse model of Prader–Willi syndrome

F Althammer, MC Wimmer, Q Krabichler… - Journal of …, 2022 - Wiley Online Library
Prader–Willi syndrome (PWS) is a neurodevelopmental disorder characterized by
hyperphagia, obesity, developmental delay and intellectual disability. Studies suggest …

[HTML][HTML] Oxytocin measurements in saliva: an analytical perspective

M López-Arjona, M Botía, S Martínez-Subiela… - BMC Veterinary …, 2023 - Springer
Oxytocin has traditionally been known for its physiological effects on muscle contraction
associated with birth and lactation, but in the last years is widely used as a biomarker of …

[HTML][HTML] Clinical and neurobiological relevance of current animal models of autism spectrum disorders

KC Kim, EL Gonzales, MT Lázaro, CS Choi… - Biomolecules & …, 2016 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social
and communication impairments, as well as repetitive and restrictive behaviors. The …

[HTML][HTML] Critical roles of serotonin-oxytocin interaction during the neonatal period in social behavior in 15q dup mice with autistic traits

M Nagano, T Takumi, H Suzuki - Scientific reports, 2018 - nature.com
Disturbance of neurotransmitters and neuromodulators is thought to underlie the
pathophysiology of autism spectrum disorder (ASD). Studies of 15q dup mouse models of …

Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability

H Meziane, M Khelfaoui, N Morello… - Human molecular …, 2016 - academic.oup.com
Loss of function mutations in human Oligophrenin1 (OPHN1) gene are responsible for
syndromic intellectual disability (ID) associated with cerebellar hypoplasia and cerebral …

[HTML][HTML] Preclinical testing in translational animal models of Prader-Willi syndrome: overview and gap analysis

KV Carias, R Wevrick - Molecular Therapy-Methods & Clinical Development, 2019 - cell.com
Prader-Willi syndrome (PWS) is a rare neurodevelopmental disorder causing endocrine,
musculoskeletal, and neurological dysfunction. PWS is caused by the inactivation of …

Environmental enrichment and intranasal oxytocin administration reverse maternal separation-induced impairments of prosocial choice behavior

S Joushi, Z Taherizadeh, K Esmaeilpour… - Pharmacology …, 2022 - Elsevier
Adverse early life experiences influence behavioral and physiological functions and
increase vulnerability to neuropsychiatric disorders. Maternal separation (MS) is an …

[HTML][HTML] Oxytocin receptor binding sites in the periphery of the neonatal mouse

MA Greenwood, EAD Hammock - PLoS One, 2017 - journals.plos.org
Oxytocin (OXT) is a pleiotropic regulator of physiology and behavior. An emerging body of
evidence demonstrates a role for OXT in the transition to postnatal life of the infant. To …

Oxytocin signaling in the early life of mammals: link to neurodevelopmental disorders associated with ASD

F Muscatelli, MG Desarménien, V Matarazzo… - Behavioral …, 2018 - Springer
Oxytocin plays a role in various functions including endocrine and immune functions but
also parent–infant bonding and social interactions. It might be considered as a main …