Intrinsically disordered proteins (IDPs) and IDP regions fail to form a stable structure, yet
they exhibit biological activities. Their mobile flexibility and structural instability are encoded …

The neural circuits governing vital behaviors, such as respiration and locomotion, are
comprised of discrete neuronal populations residing within the brainstem and spinal cord …

Principles of Nucleic Acid Structure, Second Edition, provides the most complete and
concise summary of underlying principles and approaches to studying nucleic acid structure …

Members of transcription factor families typically have similar DNA binding specificities yet
execute unique functions in vivo. Transcription factors often bind DNA as multiprotein …

It has been proposed that the Xenopus homeobox gene, XlHbox8, is involved in
endodermal differentiation during pancreatic and duodenal development (Wright, CVE …

During embryonic pattern formation, the main body axes are established and cells of
different developmental fates are specified from a single-cell zygote. Despite the …

The murine homeo box gene Nkx2-5 is expressed in precardiac mesoderm and in the
myocardium of embryonic and fetal hearts. Targeted interruption of Nkx2-5 resulted in …

We demonstrate that a mutation in the homeobox gene, MSX1, causes a common
developmental anomaly, familial tooth agenesis. Genetic linkage analyses in a family with …

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription
factor superfamily, which is characterized by the presence of a conserved DNA-binding …

The homeotic gene AGAMOUS (AG) has dual roles in specifying organ fate and limiting
stem cell proliferation in Arabidopsis flowers. We show that the floral identity protein LEAFY …