Like DNA, RNA can be designed and manipulated to produce a variety of different
nanostructures. Moreover, RNA has a flexible structure and possesses catalytic functions …

Activator protein-1 (AP-1) was first identified as a transcriptional factor that binds to an
essential cis-ele-ment of the human metallothionein lla (hMTIla) promoter [1]. AP-1 is …

T cell antigen receptor (TCR) signaling drives distinct responses depending on the
differentiation state and context of CD8+ T cells. We hypothesized that access of signal …

The unique morphological and excitable properties of nerve cells endow them with
specialized properties that permit the reception, transmission, and storage of information. It …

Basic leucine zipper transcription factor ATF-like (BATF), BATF2 and BATF3 belong to the
activator protein 1 (AP-1) family of transcription factors, which regulate numerous cellular …

Coiled-coil sequences in proteins consist of heptad repeats containing two characteristic
hydrophobic positions. The role of these buried hydrophobic residues in determining the …

The cloning of genes encoding mammalian DNA binding transcription factors for RNA
polymerase II has provided the opportunity to analyze the structure and function of these …

The yeast transcriptional activator GCN4 is 1 of over 30 identified eukaryotic proteins
containing the basic region leucine zipper (bZIP) DNA-binding motif. We have determined …

The proto-oncogenes c-fos and c-jun function cooperatively as inducible transcription factors
in signal transduction processes. Their protein products, Fos and Jun, form a heterodimeric …

THE Fos and Jun families of eukaryotic transcription factors heterodimerize to form
complexes capable of binding 5'-TGAGTCA-3'DNA elements. We have determined the X-ray …