Design of liposomes as drug delivery system for therapeutic applications
D Guimarães, A Cavaco-Paulo, E Nogueira - International journal of …, 2021 - Elsevier
Liposomes are spherical vesicles consisting of one or more concentric phospholipid bilayers
enclosing an aqueous core. Being both nontoxic and biodegradable, liposomes represent a …
enclosing an aqueous core. Being both nontoxic and biodegradable, liposomes represent a …
pH-sensitive nano-systems for drug delivery in cancer therapy
Nanotechnology has been widely used in the development of new strategies for drug
delivery and cancer therapy. Compared to traditional drug delivery systems, nano-based …
delivery and cancer therapy. Compared to traditional drug delivery systems, nano-based …
Recent advancements in polymer/liposome assembly for drug delivery: From surface modifications to hybrid vesicles
Liposomes are consolidated and attractive biomimetic nanocarriers widely used in the field
of drug delivery. The structural versatility of liposomes has been exploited for the …
of drug delivery. The structural versatility of liposomes has been exploited for the …
Chemophototherapy: an emerging treatment option for solid tumors
Near infrared (NIR) light penetrates human tissues with limited depth, thereby providing a
method to safely deliver non‐ionizing radiation to well‐defined target tissue volumes. Light …
method to safely deliver non‐ionizing radiation to well‐defined target tissue volumes. Light …
Liposomes as carriers of hydrophilic small molecule drugs: strategies to enhance encapsulation and delivery
JO Eloy, MC de Souza, R Petrilli, JPA Barcellos… - Colloids and surfaces B …, 2014 - Elsevier
Although hydrophilic small molecule drugs are widely used in the clinic, their rapid
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …
Recent advances on thermosensitive and pH-sensitive liposomes employed in controlled release
Nanotechnology has recently gained lots of interest in drug delivery due to its potential to
improve the therapeutic outcomes of various diseases. Particularly, a wide range of different …
improve the therapeutic outcomes of various diseases. Particularly, a wide range of different …
Nanocarriers' entry into the cell: relevance to drug delivery
H Hillaireau, P Couvreur - Cellular and molecular life sciences, 2009 - Springer
Nanocarriers offer unique possibilities to overcome cellular barriers in order to improve the
delivery of various drugs and drug candidates, including the promising therapeutic …
delivery of various drugs and drug candidates, including the promising therapeutic …
Nanomedicine: current status and future prospects
Applications of nanotechnology for treatment, diagnosis, monitoring, and control of
biological systems has recently been referred to as “nanomedicine” by the National Institutes …
biological systems has recently been referred to as “nanomedicine” by the National Institutes …
Pharmacokinetics and biodistribution of nanoparticles
Nanoparticles show their promise for improving the efficacy of drugs with a narrow
therapeutic window or low bioavailability, such as anticancer drugs and nucleic acid-based …
therapeutic window or low bioavailability, such as anticancer drugs and nucleic acid-based …
Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities
G Saito, JA Swanson, KD Lee - Advanced drug delivery reviews, 2003 - Elsevier
The first disulfide linkage-employing drug conjugate that exploits the reversible nature of this
unique covalent bond was recently approved for human use. Increasing numbers of drug …
unique covalent bond was recently approved for human use. Increasing numbers of drug …