Design of liposomes as drug delivery system for therapeutic applications

D Guimarães, A Cavaco-Paulo, E Nogueira - International journal of …, 2021 - Elsevier
Liposomes are spherical vesicles consisting of one or more concentric phospholipid bilayers
enclosing an aqueous core. Being both nontoxic and biodegradable, liposomes represent a …

pH-sensitive nano-systems for drug delivery in cancer therapy

J Liu, Y Huang, A Kumar, A Tan, S Jin, A Mozhi… - Biotechnology …, 2014 - Elsevier
Nanotechnology has been widely used in the development of new strategies for drug
delivery and cancer therapy. Compared to traditional drug delivery systems, nano-based …

Recent advancements in polymer/liposome assembly for drug delivery: From surface modifications to hybrid vesicles

V De Leo, F Milano, A Agostiano, L Catucci - Polymers, 2021 - mdpi.com
Liposomes are consolidated and attractive biomimetic nanocarriers widely used in the field
of drug delivery. The structural versatility of liposomes has been exploited for the …

Chemophototherapy: an emerging treatment option for solid tumors

D Luo, KA Carter, D Miranda, JF Lovell - Advanced Science, 2017 - Wiley Online Library
Near infrared (NIR) light penetrates human tissues with limited depth, thereby providing a
method to safely deliver non‐ionizing radiation to well‐defined target tissue volumes. Light …

Liposomes as carriers of hydrophilic small molecule drugs: strategies to enhance encapsulation and delivery

JO Eloy, MC de Souza, R Petrilli, JPA Barcellos… - Colloids and surfaces B …, 2014 - Elsevier
Although hydrophilic small molecule drugs are widely used in the clinic, their rapid
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …

Recent advances on thermosensitive and pH-sensitive liposomes employed in controlled release

MA Aghdam, R Bagheri, J Mosafer, B Baradaran… - Journal of controlled …, 2019 - Elsevier
Nanotechnology has recently gained lots of interest in drug delivery due to its potential to
improve the therapeutic outcomes of various diseases. Particularly, a wide range of different …

Nanocarriers' entry into the cell: relevance to drug delivery

H Hillaireau, P Couvreur - Cellular and molecular life sciences, 2009 - Springer
Nanocarriers offer unique possibilities to overcome cellular barriers in order to improve the
delivery of various drugs and drug candidates, including the promising therapeutic …

Nanomedicine: current status and future prospects

SM Moghimi, AC Hunter, JC Murray - The FASEB journal, 2005 - Wiley Online Library
Applications of nanotechnology for treatment, diagnosis, monitoring, and control of
biological systems has recently been referred to as “nanomedicine” by the National Institutes …

Pharmacokinetics and biodistribution of nanoparticles

SD Li, L Huang - Molecular pharmaceutics, 2008 - ACS Publications
Nanoparticles show their promise for improving the efficacy of drugs with a narrow
therapeutic window or low bioavailability, such as anticancer drugs and nucleic acid-based …

Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities

G Saito, JA Swanson, KD Lee - Advanced drug delivery reviews, 2003 - Elsevier
The first disulfide linkage-employing drug conjugate that exploits the reversible nature of this
unique covalent bond was recently approved for human use. Increasing numbers of drug …