Chromatin remodeling BAF (SWI/SNF) complexes in neural development and disorders
G Sokpor, Y Xie, J Rosenbusch, T Tuoc - Frontiers in molecular …, 2017 - frontiersin.org
The ATP-dependent BRG1/BRM associated factor (BAF) chromatin remodeling complexes
are crucial in regulating gene expression by controlling chromatin dynamics. Over the last …
are crucial in regulating gene expression by controlling chromatin dynamics. Over the last …
The emerging role of chromatin remodelers in neurodevelopmental disorders: a developmental perspective
B Mossink, M Negwer, D Schubert… - Cellular and Molecular …, 2021 - Springer
Neurodevelopmental disorders (NDDs), including intellectual disability (ID) and autism
spectrum disorders (ASD), are a large group of disorders in which early insults during brain …
spectrum disorders (ASD), are a large group of disorders in which early insults during brain …
Specialized subpopulations of deep-layer pyramidal neurons in the neocortex: bridging cellular properties to functional consequences
Neocortical pyramidal neurons with somata in layers 5 and 6 are among the most visually
striking and enigmatic neurons in the brain. These deep-layer pyramidal neurons (DLPNs) …
striking and enigmatic neurons in the brain. These deep-layer pyramidal neurons (DLPNs) …
A stochastic framework of neurogenesis underlies the assembly of neocortical cytoarchitecture
The cerebral cortex contains multiple areas with distinctive cytoarchitectonic patterns, but the
cellular mechanisms underlying the emergence of this diversity remain unclear. Here, we …
cellular mechanisms underlying the emergence of this diversity remain unclear. Here, we …
Development and plasticity of the corpus callosum
NS De León Reyes, L Bragg-Gonzalo… - Development, 2020 - journals.biologists.com
The corpus callosum (CC) connects the cerebral hemispheres and is the major mammalian
commissural tract. It facilitates bilateral sensory integration and higher cognitive functions …
commissural tract. It facilitates bilateral sensory integration and higher cognitive functions …
Chromatin remodeling complex NuRD in neurodevelopment and neurodevelopmental disorders
A Hoffmann, D Spengler - Frontiers in genetics, 2019 - frontiersin.org
The nucleosome remodeling and deacetylase (NuRD) complex presents one of the major
chromatin remodeling complexes in mammalian cells. Here, we discuss current evidence for …
chromatin remodeling complexes in mammalian cells. Here, we discuss current evidence for …
Mislocalisation of TDP‐43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex
Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease pathologically
characterised by mislocalisation of the RNA‐binding protein TAR‐DNA‐binding protein 43 …
characterised by mislocalisation of the RNA‐binding protein TAR‐DNA‐binding protein 43 …
A critical period of translational control during brain development at codon resolution
D Harnett, MC Ambrozkiewicz, U Zinnall… - Nature Structural & …, 2022 - nature.com
Translation modulates the timing and amplification of gene expression after transcription.
Brain development requires uniquely complex gene expression patterns, but large-scale …
Brain development requires uniquely complex gene expression patterns, but large-scale …
Transient callosal projections of L4 neurons are eliminated for the acquisition of local connectivity
Interhemispheric axons of the corpus callosum (CC) facilitate the higher order functions of
the cerebral cortex. According to current views, callosal and non-callosal fates are …
the cerebral cortex. According to current views, callosal and non-callosal fates are …
Structural and Functional Aspects of the Neurodevelopmental Gene NR2F1: From Animal Models to Human Pathology
C Tocco, M Bertacchi, M Studer - Frontiers in Molecular Neuroscience, 2021 - frontiersin.org
The assembly and maturation of the mammalian brain result from an intricate cascade of
highly coordinated developmental events, such as cell proliferation, migration, and …
highly coordinated developmental events, such as cell proliferation, migration, and …