Behavioural and dopaminergic signatures of resilience

L Willmore, C Cameron, J Yang, IB Witten, AL Falkner - Nature, 2022 - nature.com
Chronic stress can have lasting adverse consequences in some individuals, yet others are
resilient to the same stressor,. Susceptible and resilient individuals exhibit differences in the …

[PDF][PDF] Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior

MAT Vu, EH Brown, MJ Wen, CA Noggle, Z Zhang… - Neuron, 2024 - cell.com
Neural population dynamics relevant to behavior vary over multiple spatial and temporal
scales across three-dimensional volumes. Current optical approaches lack the spatial …

Inhibitory Pedunculopontine Neurons Gate Dopamine-Mediated Motor Actions of Unsigned Valence

S Zhang, J Mena-Segovia… - Current …, 2024 - ingentaconnect.com
Background: The pedunculopontine nucleus (PPN) maintains a bidirectional connectivity
with the basal ganglia that supports their shared roles in the selection and execution of …

[PDF][PDF] Lateral habenula neurons signal step-by-step changes of reward prediction

H Lee, O Hikosaka - Iscience, 2022 - cell.com
In real life, multiple objects of different values are mixed in a variety of environments. To
survive, animals need to find rewarding objects that may be located but hidden in particular …

Dopamine in the rodent tail of striatum regulates behavioral variability in response to threatening novel objects

J Pai, IE Monosov - Neuron, 2022 - cell.com
Mice display variability in fear-like responses to many external salient events, such as
encountering unexpected novel objects, but the neural basis of this variability has been …

[HTML][HTML] Opponent learning with different representations in the cortico-basal ganglia pathways can develop obsession-compulsion cycle

R Sato, K Shimomura, K Morita - PLOS Computational Biology, 2023 - journals.plos.org
Obsessive-compulsive disorder (OCD) has been suggested to be associated with
impairment of model-based behavioral control. Meanwhile, recent work suggested shorter …

Cell-type specific auditory responses in the striatum are shaped by feed forward inhibition

M Druart, M Kori, C Chaimowitz, C Fan, T Sippy - bioRxiv, 2024 - biorxiv.org
The posterior" tail" region of the striatum receives dense innervation from sensory brain
regions and has been demonstrated to play a role in behaviors that require sensorimotor …