[HTML][HTML] Pathophysiology of blood–brain barrier permeability throughout the different stages of ischemic stroke and its implication on hemorrhagic transformation and …

S Bernardo-Castro, JA Sousa, A Brás, C Cecília… - Frontiers in …, 2020 - frontiersin.org
The blood–brain barrier (BBB) is a dynamic interface responsible for maintaining the central
nervous system homeostasis. Its unique characteristics allow protecting the brain from …

[HTML][HTML] Intermittent fasting in cardiovascular disorders—an overview

B Malinowski, K Zalewska, A Węsierska… - Nutrients, 2019 - mdpi.com
Intermittent fasting is a form of time restricted eating (typically 16 h fasting and 8 h eating),
which has gained popularity in recent years and shows promise as a possible new …

Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF‐κB Suppression and NLRP3 …

Y Ran, W Su, F Gao, Z Ding, S Yang… - Oxidative medicine …, 2021 - Wiley Online Library
NLRP3 inflammasome‐mediated pyroptosis is a proinflammatory programmed cell death
pathway, which plays a vital role in functional outcomes after stroke. We previously …

[HTML][HTML] Cellular and Molecular targets for Non-Invasive, non-pharmacological Therapeutic/Rehabilitative interventions in Acute ischemic stroke

G Onose, A Anghelescu, D Blendea, V Ciobanu… - International Journal of …, 2022 - mdpi.com
BACKGROUND: Cerebral circulation delivers the blood flow to the brain through a
dedicated network of sanguine vessels. A healthy human brain can regulate cerebral blood …

[HTML][HTML] Enhancing brain plasticity to promote stroke recovery

F Su, W Xu - Frontiers in neurology, 2020 - frontiersin.org
Stroke disturbs both the structural and functional integrity of the brain. The understanding of
stroke pathophysiology has improved greatly in the past several decades. However …

[HTML][HTML] Microglial vesicles improve post-stroke recovery by preventing immune cell senescence and favoring oligodendrogenesis

S Raffaele, P Gelosa, E Bonfanti, M Lombardi… - Molecular Therapy, 2021 - cell.com
Contrasting myelin damage through the generation of new myelinating oligodendrocytes
represents a promising approach to promote functional recovery after stroke. Here, we …

[HTML][HTML] Enhancement of angiogenesis and neurogenesis by intracerebroventricular injection of secretome from human embryonic stem cell‐derived mesenchymal …

AA Taei, S Nasoohi, G Hassanzadeh, M Kadivar… - Biomedicine & …, 2021 - Elsevier
It is well accepted that the success of mesenchymal stem cells (MSCs) therapy against
experimental stroke is mainly due to cellular paracrine manners rather than to replace lost …

Paracrine effects of mesenchymal stem cells in ischemic stroke: Opportunities and challenges

A Asgari Taei, P Khodabakhsh, S Nasoohi… - Molecular …, 2022 - Springer
It is well acknowledged that neuroprotective effects of transplanted mesenchymal stem cells
(MSCs) in ischemic stroke are attributed to their paracrine-mediated actions or bystander …

Trends in NLRP3 inflammasome research in ischemic stroke from 2011 to 2022: A bibliometric analysis

H Zhu, Y Zhang, S Feng, Y Li, Y Ye… - CNS Neuroscience …, 2023 - Wiley Online Library
Background Ischemic stroke is a leading cause of permanent disability and death globally.
The nucleotide‐biding oligomaerization domain (NOD)‐like receptor family pyrin domain …

[HTML][HTML] Post-ischaemic immunological response in the brain: targeting microglia in ischaemic stroke therapy

C Rawlinson, S Jenkins, L Thei, ML Dallas, R Chen - Brain sciences, 2020 - mdpi.com
Microglia, the major endogenous immune cells of the central nervous system, mediate
critical degenerative and regenerative responses in ischaemic stroke. Microglia become …