The African continent is poised to have a pivotal role in the global population landscape,
with the United Nations projecting a population of 2.5 billion (more than 25% of the global …

Focal copy-number amplification is an oncogenic event. Although recent studies have
revealed the complex structure,–and the evolutionary trajectories of oncogene amplicons …

Ethnic or racial differences in breast cancer (BC) survival outcomes have been reported, but
current data are largely restricted to comparisons between African Americans and non …

Importance There has been little consideration of genomic risk of recurrence by breast
cancer subtype despite evidence of racial disparities in breast cancer outcomes. Objective …

Importance Among patients with breast cancer, inconsistent findings have been published
on racial disparities in achieving pathologic complete response (pCR) after neoadjuvant …

Large-scale analyses of genomic data from patients with newly diagnosed multiple myeloma
(ndMM) have been undertaken, however, large-scale analysis of relapsed/refractory MM …

Background Homologous recombination is a robust, broadly error-free mechanism of double-
strand break repair, and deficiencies lead to PARP inhibitor sensitivity. Patients displaying …

Tumor genomic profiling is increasingly seen as a prerequisite to guide the treatment of
patients with cancer. To explore the value of whole-genome sequencing (WGS) in …

Abstract In the United States, Black individuals have higher rates of cancer mortality than
any other racial group. Here, we examine chromosome copy number changes in cancers …

Race-related variation in breast cancer incidence and mortality are well-documented in the
United States. The effect of genetic ancestry on disparities in tumor genomics, risk factors …