Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

Pulmonary fibrosis (PF) is a chronic and irreversible pulmonary disease, and can lead to
decreased lung function, respiratory failure and even death. The pathogenesis research and …

Background Novel compounds and more efficient treatment options are urgently needed for
the treatment of non-small cell lung cancer (NSCLC). The decoction of Sophora flavescens …

Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Compounds with acylhydrazone fragments contain amide and imine groups that can act as
electron donors and acceptors, so they are easier to bind to biological targets and thus …

A phytochemical investigation on the alkaloids from water-soluble part of Sophora
alopecuroides led to obtain forty matrine-type alkaloids (1–40) including eighteen new ones …

Main observation and conclusion Sophaloseedlines A—G (1—7), seven new matrine‐based
alkaloids along with two known analogues, were isolated from the seeds of Sophora …

Matrine derivatives were reported to have various biological activities, especially the ester,
amide or sulfonamide derivatives of matrine deriving from the hydroxyl or carboxyl group at …

Four new alkaloids (1–4) belonging to rare examples of bis-amide matrine-type were
isolated from the seeds of sophora alopecuroides. Their structures including absolute …

Background Matrine and oxymatrine were detected in Chinese acacia honey. In order to
study their sources, some acacia honey samples from different years and producing areas …