Aryl hydrocarbon receptor as a drug target in advanced prostate cancer therapy–obstacles and perspectives
J Procházková, Z Kahounová, J Vondráček… - …, 2024 - Taylor & Francis
Aryl hydrocarbon receptor (AhR) is a transcription factor that is primarily known as an
intracellular sensor of environmental pollution. After five decades, the list of synthetic and …
intracellular sensor of environmental pollution. After five decades, the list of synthetic and …
Current status and prospects for improved targeted delivery approaches for cancer
Millions of individuals worldwide suffer from the complicated disease known as cancer.
Though they frequently have serious side effects and can harm healthy cells, the current …
Though they frequently have serious side effects and can harm healthy cells, the current …
Discovery of a small-molecule NDR1 agonist for prostate cancer therapy
Y Bai, X Sui, Z Xuan, Y Du, M Fu, Z Zheng… - Frontiers in …, 2024 - frontiersin.org
Prostatic cancer (PCa) is a common malignant neoplasm in men worldwide. Most patients
develop castration-resistant prostate cancer (CRPC) after treatment with androgen …
develop castration-resistant prostate cancer (CRPC) after treatment with androgen …
Sorafenib Encapsulated Poly (ester amide) Nanoparticles for Efficient and Biosafe Prostate Cancer Therapy
S Yu, R Zhang, Z Xie, Z Xiong, S Peng… - ACS Biomaterials …, 2024 - ACS Publications
Prostate cancer (PCa) with a high incidence worldwide is a serious threat to men's health.
Despite the continuous development of treatment strategies for PCa in recent years, the long …
Despite the continuous development of treatment strategies for PCa in recent years, the long …
Gender-affirming hormone therapy in transgender women and risk of prostate cancer: pathophysiological mechanisms and clinical implications
E Bologna, LC Licari, A Franco, F Ditonno… - Prostate Cancer and …, 2024 - nature.com
Gender-affirming hormone therapy (GAHT) for transgender women (TGW) transition is
typically based on a combination of estrogens and androgen deprivation therapy [1]. This …
typically based on a combination of estrogens and androgen deprivation therapy [1]. This …
Unveiling hormone‐stimulated gene mechanisms in prostate cancer: A prognostic model, immune infiltration analysis, and drug sensitivity study
Z Fan, Q Yu, J Deng, K Wang, H Yu… - Environmental …, 2024 - Wiley Online Library
Hormones promote the progression of prostate cancer (PRCA) through the activation of a
complex regulatory network. Inhibition of hormones or modulation of specific network nodes …
complex regulatory network. Inhibition of hormones or modulation of specific network nodes …
Mechanism of baicalein in treatment of castration-resistant prostate cancer based on network pharmacology and cell experiments
B Dou, Y Cui, Q Zhou, J Fu, Y Zhou, X Zhang… - Frontiers in …, 2024 - frontiersin.org
Objective Baicalein, one of the most abundant flavonoids found in Chinese herb Scutellaria
baicalensis Georgi, exhibits pharmacological activities against various cancers. However …
baicalensis Georgi, exhibits pharmacological activities against various cancers. However …
A New Immunotherapy Combination Promises to Improve Survival for Patients with Metastatic Prostate Cancer
JR Seremak, BL Lokeshwar - Cancers, 2023 - mdpi.com
Prostate cancer (PC) is the second-most prevalent malignancy affecting the male population
worldwide [1]. The global PC incidence in 2020 was estimated at 1.4 million new cases, with …
worldwide [1]. The global PC incidence in 2020 was estimated at 1.4 million new cases, with …