Directed evolution: methodologies and applications

Y Wang, P Xue, M Cao, T Yu, ST Lane… - Chemical reviews, 2021 - ACS Publications
Directed evolution aims to expedite the natural evolution process of biological molecules
and systems in a test tube through iterative rounds of gene diversifications and library …

Self-assembling peptide EAK16 and RADA16 nanofiber scaffold hydrogel

F Gelain, Z Luo, S Zhang - Chemical reviews, 2020 - ACS Publications
Short peptides are ubiquitous in nature. They are found as hormones, pheromones,
antibacterial and antifungal agents in innate immunity systems, toxins, and pesticides. But …

Enzyme-instructed peptide assembly favored by preorganization for cancer cell membrane engineering

Y Ding, D Zheng, L Xie, X Zhang, Z Zhang… - Journal of the …, 2023 - ACS Publications
Innovative methods for engineering cancer cell membranes promise to manipulate cell–cell
interactions and boost cell-based cancer therapeutics. Here, we illustrate an in situ …

Self‐assembled peptide‐based nanomaterials for biomedical imaging and therapy

GB Qi, YJ Gao, L Wang, H Wang - Advanced materials, 2018 - Wiley Online Library
Peptide‐based materials are one of the most important biomaterials, with diverse structures
and functionalities. Over the past few decades, a self‐assembly strategy is introduced to …

Combinatorial chemistry in drug discovery

R Liu, X Li, KS Lam - Current opinion in chemical biology, 2017 - Elsevier
Several combinatorial methods have been developed to create focused or diverse chemical
libraries with a wide range of linear or macrocyclic chemical molecules: peptides, non …

[HTML][HTML] Advancement and applications of peptide phage display technology in biomedical science

CH Wu, IJ Liu, RM Lu, HC Wu - Journal of biomedical science, 2016 - Springer
Combinatorial phage library is a powerful research tool for high-throughput screening of
protein interactions. Of all available molecular display techniques, phage display has proven …

Design of virus-based nanomaterials for medicine, biotechnology, and energy

AM Wen, NF Steinmetz - Chemical Society Reviews, 2016 - pubs.rsc.org
This review provides an overview of recent developments in “chemical virology.” Viruses, as
materials, provide unique nanoscale scaffolds that have relevance in chemical biology and …

Peptide-based imaging agents for cancer detection

X Sun, Y Li, T Liu, Z Li, X Zhang, X Chen - Advanced drug delivery reviews, 2017 - Elsevier
Selective receptor-targeting peptide based agents have attracted considerable attention in
molecular imaging of tumor cells that overexpress corresponding peptide receptors due to …

[HTML][HTML] A review of resveratrol as a potent chemoprotective and synergistic agent in cancer chemotherapy

Q Xiao, W Zhu, W Feng, SS Lee, AW Leung… - Frontiers in …, 2019 - frontiersin.org
Background: Cancer has become a major disease endangering human health around the
world. Conventional chemotherapy suffers from many side effects including pain …

Engineered living materials for advanced diseases therapy

X Dong, W Wu, P Pan, XZ Zhang - Advanced Materials, 2023 - Wiley Online Library
Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …