mTOR inhibition is most beneficial after liver transplantation for hepatocellular carcinoma in patients with active tumors

AA Schnitzbauer, N Filmann, R Adam… - Annals of …, 2020 - journals.lww.com
Objective: The aim of this study was to evaluate the survival benefit of sirolimus in patients
undergoing liver transplantation (LT) for hepatocellular carcinoma (HCC)(exploratory …

Liver transplantation for hepatocellular carcinoma: how should we improve the thresholds?

T Shimamura, R Goto, M Watanabe, N Kawamura… - Cancers, 2022 - mdpi.com
Simple Summary The ideal treatment for hepatocellular carcinoma (HCC) is liver
transplantation (LT), which both eliminates the HCC and cures the diseased liver. Once …

Liver graft rejection following immune checkpoint inhibitors treatment: a review

B Hu, XB Yang, XT Sang - Medical Oncology, 2019 - Springer
Immune checkpoint inhibitors (ICIs) have demonstrated remarkable efficacy in a variety of
solid tumors; nonetheless, they have not been well investigated and are still recognized as a …

Cost-utility analysis of imaging for surveillance and diagnosis of hepatocellular carcinoma

PH Lima, B Fan, J Bérubé, M Cerny… - American Journal of …, 2019 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study is to compare imaging-based surveillance and
diagnostic strategies in patients at risk for hepatocellular carcinoma (HCC) while taking into …

Defining the chance of cure after resection for hepatocellular carcinoma within and beyond the Barcelona Clinic Liver Cancer guidelines: A multi-institutional analysis …

DI Tsilimigras, F Bagante, D Moris, K Merath… - Surgery, 2019 - Elsevier
Background Surgery is considered the only potentially curative treatment option for patients
with hepatocellular carcinoma. However, the chance that patients will eventually be “cured” …

[HTML][HTML] Serum biomarkers and risk of hepatocellular carcinoma recurrence after liver transplantation

MJ Citores, JL Lucena, S de la Fuente… - World journal of …, 2019 - ncbi.nlm.nih.gov
Liver transplantation (LT) is the only potentially curative treatment for selected patients with
cirrhosis and hepatocellular carcinoma (HCC) who are not candidates for resection. When …

[HTML][HTML] Detection of fusion transcripts in the serum samples of patients with hepatocellular carcinoma

YP Yu, A Tsung, S Liu, M Nalesnick, D Geller… - Oncotarget, 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma is one of the most lethal cancers in the United States. Early
detection of the disease is crucial for reducing the mortality of this malignancy. Recently, we …

Can living donor liver transplantation provide similar outcomes to deceased-donor liver transplantation for hepatocellular carcinoma? A systematic review and meta …

BE Elkomos, M Abdo, R Mamdouh, A Abdelaal - Hepatology International, 2023 - Springer
Background and Aim A potential solution to the deceased organ shortage is to include live
organ donations and to identify patients with lower rates of HCC recurrence to fairly allocate …

The outcomes of systemic treatment in recurrent hepatocellular carcinomas following liver transplants

BCW Li, J Chiu, K Shing, GGW Kwok, V Tang… - Advances in …, 2021 - Springer
Background Treatment of hepatocellular carcinoma (HCC) recurrences following liver
transplant (LT) is challenging. Most clinical trials of systemic therapies for advanced HCC …

A practical nomogram from the SEER database to predict the prognosis of hepatocellular carcinoma patients with lymph node metastasis

K Zhang, C Tao, J Wu, W Rong - 2020 - researchsquare.com
Background: The presence of lymph node metastases is related to poor survival outcomes in
hepatocellular carcinoma patients and because of the reported low probability of lymph …