Noradrenergic regulation of cue-guided decision making and impulsivity is doubly dissociable across frontal brain regions
CS Chernoff, TJ Hynes, JD Schumacher… - …, 2024 - Springer
Rationale Win-paired stimuli can promote risk taking in experimental gambling paradigms in
both rats and humans. We previously demonstrated that atomoxetine, a noradrenaline …
both rats and humans. We previously demonstrated that atomoxetine, a noradrenaline …
Repeated Cocaine Intake Differentially Impacts Striatal D2/3 Receptor Availability, Psychostimulant-Induced Dopamine Release, and Trait Behavioral Markers of …
G Urueña-Méndez, A Dimiziani, L Bellés… - International Journal of …, 2023 - mdpi.com
Current research indicates that altered dopamine (DA) transmission in the striatum
contributes to impulsivity and novelty-seeking, and it may mediate a link concerning a higher …
contributes to impulsivity and novelty-seeking, and it may mediate a link concerning a higher …
Prelimbic cortex activity during a distress tolerance task predicts cocaine-seeking behavior in male, but not female rats
TM Moschak, TJ Sloand, RM Carelli - Journal of Neuroscience, 2023 - Soc Neuroscience
Distress tolerance (DT) is defined as the ability to persist in challenging goal-directed
behavior in the face of stress, and individuals with low DT exhibit heightened drug-seeking …
behavior in the face of stress, and individuals with low DT exhibit heightened drug-seeking …
Activation of the mPFC-NAc pathway reduces motor impulsivity but does not affect risk-related decision-making in innately high-impulsive rats
C Arrondeau, G Urueña-Méndez, F Marchessaux… - bioRxiv, 2024 - biorxiv.org
Attention-deficit/hyperactivity disorder (ADHD) and substance use disorders (SUD) are
characterized by exacerbated motor and risk-related impulsivities, which are associated with …
characterized by exacerbated motor and risk-related impulsivities, which are associated with …
RECORD: A high-throughput system for complex naturalistic decision-making in rodents
A Friedman, R Ibanez-Alcala, D Beck, A Salcido… - 2023 - researchsquare.com
Translational studies benefit from experimental designs where laboratory organisms use
human-relevant behaviors. One such behavior is decision-making, however studying …
human-relevant behaviors. One such behavior is decision-making, however studying …
Dissociating the role of prefrontal noradrenaline signaling in cost-benefit decision making and impulsive action
C Chernoff - 2023 - open.library.ubc.ca
Win-paired stimuli can promote risk taking on experimental gambling paradigms in both rats
and humans. We previously demonstrated that atomoxetine, a noradrenaline reuptake …
and humans. We previously demonstrated that atomoxetine, a noradrenaline reuptake …
Psychobiological Mechanisms of Maladaptive Cocaine Seeking
D Conlisk - 2022 - theses.hal.science
About 20% of cocaine users suffer with severe cocaine use disorder (CUD) or addiction, and
to date, there are limited therapeutic options available. Due to this, there is an increased …
to date, there are limited therapeutic options available. Due to this, there is an increased …
[图书][B] Dysregulation of Behavioral Control of Impulsivity
KK Bodinayake - 2023 - search.proquest.com
The capacity for top-down control is thought to contribute to the maladaptive and impulsive
reward seeking seen in a number of neuropsychiatric disorders, including drug addiction …
reward seeking seen in a number of neuropsychiatric disorders, including drug addiction …