Aggressive pituitary tumors and pituitary carcinomas: from pathology to treatment

P Burman, O Casar-Borota… - The Journal of …, 2023 - academic.oup.com
Aggressive pituitary tumors (APTs) and pituitary carcinomas (PCs) are heterogeneous with
regard to clinical presentation, proliferative markers, clinical course, and response to …

[HTML][HTML] A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization …

G Rindi, DS Klimstra, B Abedi-Ardekani, SL Asa… - Modern Pathology, 2018 - Elsevier
The classification of neuroendocrine neoplasms (NENs) differs between organ systems and
currently causes considerable confusion. A uniform classification framework for NENs at any …

The epidemiology of aggressive pituitary tumors (and its challenges)

OM Dekkers, N Karavitaki, AM Pereira - Reviews in Endocrine and …, 2020 - Springer
Pituitary tumors are not rare if prevalence rates from autopsy or radiological series are
considered; approximately 0.5% of all pituitary adenomas will come to medical attention …

Pituitary tumors: epidemiology and clinical presentation spectrum

M Araujo-Castro, VR Berrocal, E Pascual-Corrales - Hormones, 2020 - Springer
Pituitary tumors (PTs) are a heterogeneous group of lesions of the central nervous system
that are usually benign. Most of them occur sporadically, but 5% can do so within family …

An institutional experience of tumor progression to pituitary carcinoma in a 15-year cohort of 1055 consecutive pituitary neuroendocrine tumors

OM Alshaikh, SL Asa, O Mete, S Ezzat - Endocrine pathology, 2019 - Springer
Pituitary carcinoma is a rare disease, defined by the presence of cerebrospinal or distant
metastasis of a pituitary neuroendocrine tumor (PitNET). To review our institutional …

Recurrence of silent corticotroph adenomas after primary treatment: a systematic review and meta-analysis

A Fountas, A Lavrentaki, A Subramanian… - The Journal of …, 2019 - academic.oup.com
Abstract Context The 2017 WHO Classification of Pituitary Tumors grades silent corticotroph
adenomas (SCAs) as “high-risk adenomas” due to their aggressive clinical behavior (high …

[HTML][HTML] Non-functioning pituitary adenomas

JB Drummond, A Ribeiro-Oliveira Jr… - Endotext [Internet], 2022 - ncbi.nlm.nih.gov
ABSTRACT Pituitary adenomas comprise approximately 10-20% of intracranial tumors. Non-
functioning pituitary adenomas (NFPAs) are benign adenohypophyseal tumors not …

Aggressive and malignant pituitary tumours: state-of-the-art

D Dworakowska, AB Grossman - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Pituitary adenomas are unique in multiple ways. They are rarely malignant in terms of
metastases; yet, they may be aggressive. Their cancerous potential is defined in a classic …

[HTML][HTML] Aggressive pituitary tumors (PitNETs)

H Nishioka - Endocrine journal, 2023 - jstage.jst.go.jp
The majority of anterior pituitary tumors behave benignly, that is, they grow slowly and do not
metastasize, and were therefore called adenomas. However, they would frequently invade …

[HTML][HTML] Regulating the CCNB1 gene can affect cell proliferation and apoptosis in pituitary adenomas and activate epithelial‑to‑mesenchymal transition

B Li, HB Zhu, GD Song, JH Cheng, CZ Li… - Oncology …, 2019 - spandidos-publications.com
The aim of the present study was to investigate the role and potential regulatory
mechanisms of cyclin B1 (CCNB1) in the proliferation, apoptosis and epithelial‑to …