Hyaluronic acid: A key ingredient in the therapy of inflammation

A Marinho, C Nunes, S Reis - Biomolecules, 2021 - mdpi.com
Hyaluronic acid (HA) is a natural polymer, produced endogenously by the human body,
which has unique physicochemical and biological properties, exhibiting desirable …

Advances in multifunctional chitosan-based self-healing hydrogels for biomedical applications

Y Ou, M Tian - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Multifunctional self-healing hydrogels have recently attracted considerable interest in
biomedical applications owing to their diverse properties, including self-healing, adhesion …

Functional biomaterials for osteoarthritis treatment: from research to application

Y Lei, Q Zhang, G Kuang, X Wang, Q Fan… - Smart Medicine, 2022 - Wiley Online Library
Osteoarthritis (OA) is a common disease that endangers millions of middle‐aged and elderly
people worldwide. Researchers from different fields have made great efforts and achieved …

A multifunctional chitosan-based hydrogel with self-healing, antibacterial, and immunomodulatory effects as wound dressing

Q Yu, Y Yan, J Huang, Q Liang, J Li, B Wang… - International Journal of …, 2023 - Elsevier
Bacterial infection often leads to inflammatory responses and delays wound healing.
Chitosan (CS)-based composite hydrogels can hold desirable mechanical properties and …

Application of chitosan with different molecular weights in cartilage tissue engineering

R Zhang, SJ Chang, Y Jing, LY Wang, CJ Chen… - Carbohydrate …, 2023 - Elsevier
Cartilage tissue engineering involves the invention of novel implantable cartilage
replacement materials to help heal cartilage injuries that do not heal themselves, aiming to …

Injectable chitosan-based self-healing supramolecular hydrogels with temperature and pH dual-responsivenesses

Y Yang, G Feng, J Wang, R Zhang, S Zhong… - International Journal of …, 2023 - Elsevier
In this study, a supramolecular hydrogel was fabricated with orotic acid (OA) modified
chitosan (OACS) and 2, 6-diaminopurine (DAP). The obtained OACS-DAP supramolecular …

Polymeric hydrogels for controlled drug delivery to treat arthritis

A Gupta, J Lee, T Ghosh, VQ Nguyen, A Dey, B Yoon… - Pharmaceutics, 2022 - mdpi.com
Rheumatoid arthritis (RA) and osteoarthritis (OA) are disabling musculoskeletal disorders
that affect joints and cartilage and may lead to bone degeneration. Conventional delivery of …

Recent developments and current applications of hydrogels in osteoarthritis

T Zhao, Z Wei, W Zhu, X Weng - Bioengineering, 2022 - mdpi.com
Osteoarthritis (OA) is a common degenerative joint disease that causes disability if left
untreated. The treatment of OA currently requires a proper delivery system that avoids the …

Preparation and characterizations of antibacterial and electroactive polymeric composites for wound healing applications

G Unnikrishnan, A Joy, M Megha, J Thomas… - Polymer …, 2024 - Wiley Online Library
Polymer nanocomposites have been utilized for wound healing applications. Compared to
the conventional polymer composites, conducting polymer nanocomposites comprising a …

Drug delivery systems for the treatment of knee osteoarthritis: a systematic review of in vivo studies

FM Gambaro, A Ummarino, F Torres Andon… - International Journal of …, 2021 - mdpi.com
Many efforts have been made in the field of nanotechnology to improve the local and
sustained release of drugs, which may be helpful to overcome the present limitations in the …