Technological innovations in photochemistry for organic synthesis: flow chemistry, high-throughput experimentation, scale-up, and photoelectrochemistry

L Buglioni, F Raymenants, A Slattery… - Chemical …, 2021 - ACS Publications
Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …

The concept of chemical generators: on-site on-demand production of hazardous reagents in continuous flow

D Dallinger, B Gutmann, CO Kappe - Accounts of chemical …, 2020 - ACS Publications
Conspectus In recent years, a steadily growing number of chemists, from both academia and
industry, have dedicated their research to the development of continuous flow processes …

[HTML][HTML] Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer

Y Kim, J Heo, D Kim, S Chang, S Seo - Nature Communications, 2020 - nature.com
Chemical synthesis based on the skeletal variation has been prolifically utilized as an
attractive approach for modification of molecular properties. Given the ubiquity of unstrained …

Flow chemistry: a sustainable voyage through the chemical universe en route to smart manufacturing

AA Volk, ZS Campbell, MYS Ibrahim… - Annual Review of …, 2022 - annualreviews.org
Microfluidic devices and systems have entered many areas of chemical engineering, and
the rate of their adoption is only increasing. As we approach and adapt to the critical global …

[HTML][HTML] GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design

C Castiello, P Junghanns, A Mergel, C Jacob… - Green …, 2023 - pubs.rsc.org
Green chemistry has become a hot topic and the focus of not only many companies but also
researchers. Green chemistry strives to identify alternative and environmentally friendly …

Forgotten and forbidden chemical reactions revitalised through continuous flow technology

A Bonner, A Loftus, AC Padgham… - Organic & Biomolecular …, 2021 - pubs.rsc.org
Continuous flow technology has played an undeniable role in enabling modern chemical
synthesis, whereby a myriad of reactions can now be performed with greater efficiency …

Will the next generation of chemical plants be in miniaturized flow reactors?

JCM Monbaliu, J Legros - Lab on a Chip, 2023 - pubs.rsc.org
For decades, a production paradigm based on centralized, stepwise, large scale processes
has dominated the chemical industry horizon. While effective to meet an ever increasing …

The chemistry and biology of guanidine secondary metabolites

RGS Berlinck, DI Bernardi, T Fill… - Natural Product …, 2021 - pubs.rsc.org
Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …

[HTML][HTML] Continuous photochemical benzylic bromination using in situ generated Br 2: process intensification towards optimal PMI and throughput

A Steiner, JD Williams, O De Frutos, JA Rincón… - Green chemistry, 2020 - pubs.rsc.org
The detailed development of photochemical benzylic brominations using a NaBrO3/HBr
bromine generator in continuous flow mode is reported. Optimization of the bromine …

Functionalized MIL-68 (In) for the photocatalytic treatment of Cr (VI)-containing simulation wastewater: Electronic effects of ligand substitution

R Liang, R Huang, X Wang, S Ying, G Yan, L Wu - Applied Surface Science, 2019 - Elsevier
A family of functionalized MIL-68 (In) have been successfully synthesized and applied to
photoreduction of Cr (VI) aqueous under simulated sunlight (280 nm< λ< 980 nm) …