Carbohydrate-based macromolecular biomaterials
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …
[HTML][HTML] Recent advances in polysaccharides based biomaterials for drug delivery and tissue engineering applications
In this paper, a spotlight is shown on polysaccharides based biomaterials which have
surfaced as a versatile platform for different biomedical applications including drug delivery …
surfaced as a versatile platform for different biomedical applications including drug delivery …
[HTML][HTML] Intercellular mitochondria transfer to macrophages regulates white adipose tissue homeostasis and is impaired in obesity
Recent studies suggest that mitochondria can be transferred between cells to support the
survival of metabolically compromised cells. However, whether intercellular mitochondria …
survival of metabolically compromised cells. However, whether intercellular mitochondria …
Pharmacology of heparin and related drugs: An update
J Hogwood, B Mulloy, R Lever, E Gray, CP Page - Pharmacological reviews, 2023 - ASPET
Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …
[HTML][HTML] Biomedical applications of engineered heparin-based materials
Heparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic
backbone. Due to its fascinating chemical and physical properties, nontoxicity …
backbone. Due to its fascinating chemical and physical properties, nontoxicity …
Heparin: An old drug for new clinical applications
P Wang, L Chi, Z Zhang, H Zhao, F Zhang… - Carbohydrate …, 2022 - Elsevier
Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …
[HTML][HTML] CK2 regulation: perspectives in 2021
SE Roffey, DW Litchfield - Biomedicines, 2021 - mdpi.com
The protein kinase CK2 (CK2) family encompasses a small number of acidophilic
serine/threonine kinases that phosphorylate substrates involved in numerous biological …
serine/threonine kinases that phosphorylate substrates involved in numerous biological …
Polysaccharide–peptide conjugates: a versatile material platform for biomedical applications
HQ Song, Y Fan, Y Hu, G Cheng… - Advanced Functional …, 2021 - Wiley Online Library
Natural polymers, such as polysaccharides and proteins, have been widely studied for
numerous biomedical applications because of their bioactivity, natural origin, and …
numerous biomedical applications because of their bioactivity, natural origin, and …
[HTML][HTML] The anticoagulant and nonanticoagulant properties of heparin
DMH Beurskens, JP Huckriede… - Thrombosis and …, 2020 - thieme-connect.com
Heparins represent one of the most frequently used pharmacotherapeutics. Discovered
around 1926, routine clinical anticoagulant use of heparin was initiated only after the …
around 1926, routine clinical anticoagulant use of heparin was initiated only after the …
Glycosaminoglycans from marine sources as therapeutic agents
J Valcarcel, R Novoa-Carballal, RI Pérez-Martín… - Biotechnology …, 2017 - Elsevier
Glycosaminoglycans (GAGs) in marine animals are different to those of terrestrial organisms,
mainly in terms of molecular weight and sulfation. The therapeutic properties of GAGs are …
mainly in terms of molecular weight and sulfation. The therapeutic properties of GAGs are …