Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

In this paper, a spotlight is shown on polysaccharides based biomaterials which have
surfaced as a versatile platform for different biomedical applications including drug delivery …

Recent studies suggest that mitochondria can be transferred between cells to support the
survival of metabolically compromised cells. However, whether intercellular mitochondria …

Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …

Heparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic
backbone. Due to its fascinating chemical and physical properties, nontoxicity …

Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …

The protein kinase CK2 (CK2) family encompasses a small number of acidophilic
serine/threonine kinases that phosphorylate substrates involved in numerous biological …

Natural polymers, such as polysaccharides and proteins, have been widely studied for
numerous biomedical applications because of their bioactivity, natural origin, and …

Heparins represent one of the most frequently used pharmacotherapeutics. Discovered
around 1926, routine clinical anticoagulant use of heparin was initiated only after the …

Glycosaminoglycans (GAGs) in marine animals are different to those of terrestrial organisms,
mainly in terms of molecular weight and sulfation. The therapeutic properties of GAGs are …