Diabetic kidney disease (DKD) can occur in approximately 30–40% of both type 1 and type
2 diabetic patients. The well-established features of DKD include increased serum glucose …

The IL-1 superfamily of cytokines is a central regulator of immunity and inflammation. The
family is composed of 11 cytokines (with agonist, antagonist, and anti-inflammatory …

From birth onward, the lungs are exposed to the external environment and therefore harbor
a complex immunological milieu to protect this organ from damage and infection. We …

The alarmin IL-33 is an IL-1 family member that stimulates pleiotropic immune reactions
depending on the target tissue and microenvironmental factors. In this study, we have …

Objective Intraamniotic inflammation/infection is the only mechanism of disease with
persuasive evidence of causality for spontaneous preterm labor/delivery. Previous studies …

Background Myocarditis is an important cause of acute and chronic heart failure. Men with
myocarditis have worse recovery and an increased need for transplantation compared with …

Atherosclerotic vascular disease remains the most common cause of ischemia, myocardial
infarction, and stroke. Vascular function is determined by structural and functional properties …

Interleukin (IL)-33 and its unique receptor, ST2, play a pivotal role in the immune response
to infection and stress. However, there have been conflicting reports of the role of IL-33 in …

Cell stemness is characterized by quiescence, pluripotency, and long-term self-renewal
capacity. Therapy-resistant leukemic stem cells (LSCs) are the primary cause of relapse in …

Abstract Purpose of Review In this review, we discuss the evidence supporting the effects of
statins on mast cells (MCs) in atherosclerosis and their molecular mechanism of action …