Oral nanomedicine: challenges and opportunities
Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …
infection, and complications and has a higher compliance rate for patients with diverse …
Marine biomaterials in biomedical nano/micro-systems
Y Wang, L Chen, Y Wang, X Wang, D Qian… - Journal of …, 2023 - Springer
Marine resources in unique marine environments provide abundant, cost-effective natural
biomaterials with distinct structures, compositions, and biological activities compared to …
biomaterials with distinct structures, compositions, and biological activities compared to …
Engineering the intestinal lymphatic transport of oral nanoparticles to educate macrophages for cancer combined immunotherapy
L Xu, S Weng, S Li, K Wang, Y Shen, Y Xu, C Tang… - ACS …, 2023 - ACS Publications
The effectiveness of the commonly used therapy is low for treating triple-negative breast
cancer (TNBC). Macrophages, accounting for up to 50% of the TNBC tumor mass, are …
cancer (TNBC). Macrophages, accounting for up to 50% of the TNBC tumor mass, are …
Fluorocarbon modified chitosan to enable transdermal immunotherapy for melanoma treatment
Q Zhuang, T Chao, Y Wu, T Wei, J Ren, Z Cao, R Peng… - Small, 2023 - Wiley Online Library
Despite the rapid development of the immune checkpoint blockade (ICB) in melanoma
treatment, the immunosuppressive tumor microenvironment (TME) still hinders the efficacy of …
treatment, the immunosuppressive tumor microenvironment (TME) still hinders the efficacy of …
Lipid-and polymer-based nanocarrier platforms for cancer vaccine delivery
Cancer immunotherapy has gained popularity in recent years in the search for effective
treatment modalities for various malignancies, particularly those that are resistant to …
treatment modalities for various malignancies, particularly those that are resistant to …
Systemic delivery of proteins using novel peptides via the sublingual route
Therapeutic proteins often require needle-based injections, which compromise medication
adherence especially for those with chronic diseases. Sublingual administration provides a …
adherence especially for those with chronic diseases. Sublingual administration provides a …
Functional chitosan and its derivative-related drug delivery systems for nano-therapy: recent advances
Z Wang, F Yu, F Hu - Pharmaceutics, 2024 - mdpi.com
In the struggle against diseases, the development of nano-therapy has certainly been a
tremendous progression owing to the various superiority, and chitosan is no doubt a kind of …
tremendous progression owing to the various superiority, and chitosan is no doubt a kind of …
Transmucosal delivery of nasal nanovaccines enhancing mucosal and systemic immunity
Y Xu, X Yan, T Wei, M Chen, J Zhu, J Gao, B Liu… - Nano Letters, 2023 - ACS Publications
Intranasal vaccines can induce protective immune responses at the mucosa surface
entrance, preventing the invasion of respiratory pathogens. However, the nasal barrier …
entrance, preventing the invasion of respiratory pathogens. However, the nasal barrier …
Progress in chitin/chitosan and their derivatives for biomedical applications: Where we stand
L Mu, L Wu, S Wu, Q Ye, Z Zhong - Carbohydrate Polymers, 2024 - Elsevier
Chitin and its deacetylated form, chitosan, have demonstrated remarkable versatility in the
realm of biomaterials. Their exceptional biocompatibility, antibacterial properties, pro-and …
realm of biomaterials. Their exceptional biocompatibility, antibacterial properties, pro-and …
Oral mitochondrial transplantation using nanomotors to treat ischaemic heart disease
Z Wu, L Chen, W Guo, J Wang, H Ni, J Liu… - Nature …, 2024 - nature.com
Mitochondrial transplantation is an important therapeutic strategy for restoring energy supply
in patients with ischaemic heart disease (IHD); however, it is limited by the invasiveness of …
in patients with ischaemic heart disease (IHD); however, it is limited by the invasiveness of …