The artificial lung (AL) technology is one of the membrane-based artificial organs that partly
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …

The short‐and long‐term thrombogenicity of implant materials is still unpredictable, which is
a significant challenge for the treatment of cardiovascular diseases. A knowledge‐based …

Purpose Device-induced blood damage contributes the hemolysis, thrombosis and bleeding
complications in patients supported with ventricular assist device (VAD). This study aims to …

Background Extracorporeal membrane oxygenation (ECMO) is a life-saving modality used
to manage cardiopulmonary failure refractory to conventional medical and surgical …

Objective: Mechanical circulatory support has emerged as lifesaving therapy for patients
with advanced heart failure. However, mechanical circulatory support remains limited by a …

Despite decades of technological advancements in blood-contacting medical devices,
complications related to shear flow-induced blood trauma are still frequently observed in …

Purpose To develop a mathematical model for predicting shear-induced von Willebrand
factor (vWF) function modification which can be used to guide ventricular assist devices …

A plethora of leukocyte modulations have been reported in critically ill patients. Critical
illnesses such as acute respiratory distress syndrome and cardiogenic shock, which …

Despite growing use of mechanical circulatory support, limitations remain related to
hemocompatibility. Here, we performed a head-to-head comparison of the …

Purpose The objective of this study is to develop a bleeding risk model for assessing device-
induced bleeding risk in patients supported with blood contact medical devices (BCMDs) …