Hemocompatibility challenge of membrane oxygenator for artificial lung technology
The artificial lung (AL) technology is one of the membrane-based artificial organs that partly
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …
In vitro thrombogenicity testing of biomaterials
S Braune, RA Latour, M Reinthaler… - Advanced …, 2019 - Wiley Online Library
The short‐and long‐term thrombogenicity of implant materials is still unpredictable, which is
a significant challenge for the treatment of cardiovascular diseases. A knowledge‐based …
a significant challenge for the treatment of cardiovascular diseases. A knowledge‐based …
Multi-indicator analysis of mechanical blood damage with five clinical ventricular assist devices
Purpose Device-induced blood damage contributes the hemolysis, thrombosis and bleeding
complications in patients supported with ventricular assist device (VAD). This study aims to …
complications in patients supported with ventricular assist device (VAD). This study aims to …
Low flow rate alters haemostatic parameters in an ex-vivo extracorporeal membrane oxygenation circuit
KK Ki, MR Passmore, CHH Chan… - Intensive care medicine …, 2019 - Springer
Background Extracorporeal membrane oxygenation (ECMO) is a life-saving modality used
to manage cardiopulmonary failure refractory to conventional medical and surgical …
to manage cardiopulmonary failure refractory to conventional medical and surgical …
Platelet Dysfunction During Mechanical Circulatory Support: Elevated Shear Stress Promotes Downregulation of αIIbβ3 and GPIb via Microparticle Shedding …
Y Roka-Moiia, S Miller-Gutierrez… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Mechanical circulatory support has emerged as lifesaving therapy for patients
with advanced heart failure. However, mechanical circulatory support remains limited by a …
with advanced heart failure. However, mechanical circulatory support remains limited by a …
[HTML][HTML] Discrete responses of erythrocytes, platelets, and von Willebrand factor to shear
CHH Chan, MJ Simmonds, KH Fraser, K Igarashi… - Journal of …, 2022 - Elsevier
Despite decades of technological advancements in blood-contacting medical devices,
complications related to shear flow-induced blood trauma are still frequently observed in …
complications related to shear flow-induced blood trauma are still frequently observed in …
Development and validation of a mathematical model for evaluating shear-induced damage of von Willebrand factor
Y Li, Y Xi, H Wang, A Sun, L Wang, X Deng… - Computers in Biology …, 2023 - Elsevier
Purpose To develop a mathematical model for predicting shear-induced von Willebrand
factor (vWF) function modification which can be used to guide ventricular assist devices …
factor (vWF) function modification which can be used to guide ventricular assist devices …
Current understanding of leukocyte phenotypic and functional modulation during extracorporeal membrane oxygenation: a narrative review
A plethora of leukocyte modulations have been reported in critically ill patients. Critical
illnesses such as acute respiratory distress syndrome and cardiogenic shock, which …
illnesses such as acute respiratory distress syndrome and cardiogenic shock, which …
[HTML][HTML] Impella 5.5 versus Centrimag: a head-to-head comparison of device hemocompatibility
Y Roka-Moiia, M Li, A Ivich, S Muslmani, KB Kern… - Asaio …, 2020 - journals.lww.com
Despite growing use of mechanical circulatory support, limitations remain related to
hemocompatibility. Here, we performed a head-to-head comparison of the …
hemocompatibility. Here, we performed a head-to-head comparison of the …
A mathematical model for assessing shear induced bleeding risk
Y Li, H Wang, Y Xi, A Sun, L Wang, X Deng… - Computer Methods and …, 2023 - Elsevier
Purpose The objective of this study is to develop a bleeding risk model for assessing device-
induced bleeding risk in patients supported with blood contact medical devices (BCMDs) …
induced bleeding risk in patients supported with blood contact medical devices (BCMDs) …