[HTML][HTML] Epigenetic crosstalk between Malignant plasma cells and the tumour microenvironment in multiple myeloma

A Allegra, M Casciaro, P Barone, C Musolino… - Cancers, 2022 - mdpi.com
Simple Summary Multiple myeloma is a haematological malignancy due to a proliferation of
clonal plasma cells. The medullary milieu consists of a bone marrow microenvironment …

[HTML][HTML] МНОЖЕСТВЕННОЙ МИЕЛОМЫ: ДИАГНОСТИКА И ТЕРАПИЯ (ЧАСТЬ 2)

СС Бессмельцев - Вестник гематологии, 2022 - cyberleninka.ru
Использование новых подходов в лечении рецидивов и рефрактерных форм
множественной миеломы (ММ) привело к существенному улучшению общей …

Impact of treatment sequencing on overall survival in patients with transplant-ineligible newly diagnosed myeloma

R Fonseca, T Facon, M Hashim, S Nair, J He… - The …, 2023 - academic.oup.com
Background Because patients with newly diagnosed multiple myeloma (NDMM) do not
always receive any treatment beyond first-line (1L) therapy, it is imperative that patients …

[HTML][HTML] Minimal residual disease detection by next-generation sequencing in multiple myeloma: Promise and challenges for response-adapted therapy

V Ferla, E Antonini, T Perini, F Farina… - Frontiers in …, 2022 - frontiersin.org
Assessment of minimal residual disease (MRD) is becoming a standard diagnostic tool for
curable hematological malignancies such as chronic and acute myeloid leukemia. Multiple …

Role of daratumumab in the frontline management of multiple myeloma: a narrative review

S Yadav, S Gundeti, A Bhave, U Deb… - Expert Review of …, 2023 - Taylor & Francis
Introduction The prevalence of multiple myeloma (MM) has gradually increased over the last
few decades in India due to growing population, better disease awareness, and improved …

[HTML][HTML] Daratumumab-based immunotherapy vs. lenalidomide, bortezomib and dexamethasone in transplant-ineligible newly diagnosed multiple myeloma: a …

W Tang, L Zhang, Y Zheng, L Pan, T Niu - Frontiers in Oncology, 2024 - ncbi.nlm.nih.gov
Background Since no randomized controlled trials have directly compared the efficacy and
safety of immunotherapy with daratumumab versus lenalidomide/bortezomib …

[HTML][HTML] Adjusted Indirect Treatment Comparison of Progression-Free Survival with D-Rd and VRd Based on MAIA and SWOG S0777 Individual Patient-Level Data

BGM Durie, SK Kumar, EM Ammann, AZ Fu, S Kaila… - Advances in …, 2024 - Springer
Introduction Daratumumab plus lenalidomide and dexamethasone (D-Rd) and bortezomib
plus lenalidomide and dexamethasone (VRd) are commonly used treatment combinations …

Comparisons of efficacy between frontline treatment with bortezomib-melphalan-prednisone and lenalidomide-dexamethasone for transplant-ineligible multiple …

JY Lee, SS Park, YW Jeon, SH Shin, SA Yahng… - Journal of Cancer …, 2023 - Springer
Background Bortezomib-melphalan-prednisone (VMP) and lenalidomide-dexamethasone
(Rd) remain the standard treatments for transplant-ineligible patients with newly diagnosed …

Clinical consensus on treatments for transplant-ineligible newly diagnosed multiple myeloma: double-blinded Delphi panel

R Fonseca, A Rossi, R Medhekar, J Voelker… - Future …, 2024 - Taylor & Francis
Aim: Obtain clinical consensus on factors impacting first-line prescribing for transplant-
ineligible (TIE) patients with newly diagnosed multiple myeloma (NDMM). Materials & …

Quadruplet regimen for newly diagnosed multiple myeloma is effective in the standard-risk subgroup but not in the high-risk subgroup

J Ding, S Gong - Frontiers in Pharmacology, 2024 - frontiersin.org
Multiple myeloma (MM) is the second most common hematologic cancer, with an estimated
35,730 new cases and 12,590 deaths annually in the United States (Siegel et al., 2023) …