Despite the recent advances in cancer therapy, triple-negative breast cancers (TNBCs) are
the most relapsing cancer sub-type. It is partly due to their propensity to develop resistance …

Cancer is initiated largely by specific cohorts of genetic aberrations, which are generated by
mutagens and often mimic active growth factor receptors, or downstream effectors. Once …

Background There is growing evidence that endocytosis plays a pivotal role in cancer
metastasis. In this study, we first identified endocytic and metastasis‐associated genes …

Transcription factor CP2c (also known as TFCP2, α-CP2, LSF, and LBP-1c) is involved in
diverse ubiquitous and tissue/stage-specific cellular processes and in human malignancies …

An example of a mandibular rhabdomyosarcoma in a 15-year-old male is described
featuring EWSR1-TFCP2 fusion with homolateral lymph node metastasis and apparent …

MAF amplification increases the risk of breast cancer (BCa) metastasis through mechanisms
that are still poorly understood yet have important clinical implications. Oestrogen-receptor …

Proteins play a crucial role in many biological processes, where their interaction with other
proteins are integral. Abnormal protein-protein interactions (PPIs) have been linked to …

Abstract Background Integrin alpha 2 (ITGA2) has been recently reported to be an oncogene
and to play crucial roles in tumor cell proliferation, invasion, metastasis, and angiogenesis …

Immunotherapy represented by programmed cell death protein 1 (PD-1)/programmed death
ligand 1 (PD-L1) monoclonal antibodies has led tumor treatment into a new era. However …

CP2c, also known as TFCP2, α-CP2, LSF, and LBP-1c, is a prototypic member of the
transcription factor (TF) CP2 subfamily involved in diverse ubiquitous and tissue/stage …