HIV-1 drug resistance genotyping in resource limited settings: current and future perspectives in sequencing technologies
Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …
Precise and programmable detection of mutations using ultraspecific riboregulators
The ability to identify single-nucleotide mutations is critical for probing cell biology and for
precise detection of disease. However, the small differences in hybridization energy …
precise detection of disease. However, the small differences in hybridization energy …
Antimicrobial Resistance in the WHO African Region: a systematic literature review
World Health Organization - … in the WHO African Region: a …, 2021 - pesquisa.bvsalud.org
Antimicrobial resistance in the WHO African Region: a systematic literature review | Brazzaville;
World Health Organization. Regional Office for Africa; 2021. | WHOLIS loading Conteúdo …
World Health Organization. Regional Office for Africa; 2021. | WHOLIS loading Conteúdo …
Laboratory Based Surveillance of HIV-1 Acquired Drug Resistance in Cameroon: Implications for Use of Tenofovir-Lamivudine-Dolutegravir (TLD) as Second-or Third …
J Fokam, CA Chenwi, D Takou, MM Santoro, V Tala… - Viruses, 2023 - mdpi.com
Increased HIV drug resistance (HIVDR) with antiretroviral therapy (ART) rollout may
jeopardize therapeutic options, especially in this era of transition to fixed-dose tenofovir …
jeopardize therapeutic options, especially in this era of transition to fixed-dose tenofovir …
Evaluation of treatment response, drug resistance and HIV-1 variability among adolescents on first-and second-line antiretroviral therapy: a study protocol for a …
J Fokam, MM Santoro, D Takou, AE Njom-Nlend… - BMC pediatrics, 2019 - Springer
Abstract Background Sub-Saharan Africa (SSA) alone has nine out of every 10 children
living with HIV globally and monitoring in this setting remains suboptimal, even as these …
living with HIV globally and monitoring in this setting remains suboptimal, even as these …
SARS-CoV-2 genomic surveillance and reliability of PCR single point mutation assay (SNPsig® SARS-CoV-2 EscapePLEX CE) for the rapid detection of variants of …
J Fokam, DHG Anguechia, D Takou, ENJ Semengue… - Heliyon, 2024 - cell.com
Abstract Background Surveillance of SARS-CoV-2 variants of concern (VOCs) and lineages
is crucial for decision-making. Our objective was to study the SARS-CoV-2 clade dynamics …
is crucial for decision-making. Our objective was to study the SARS-CoV-2 clade dynamics …
HIV-1 integrase resistance associated mutations and the use of dolutegravir in Sub-Saharan Africa: A systematic review and meta-analysis
E Ngoufack Jagni Semengue, MM Santoro… - PLOS global public …, 2022 - journals.plos.org
As sub-Saharan Africa (SSA) countries are transitioning to dolutegravir (DTG)-based ART,
baseline data are required for optimal monitoring of therapeutic response. In this frame, we …
baseline data are required for optimal monitoring of therapeutic response. In this frame, we …
Higher iron stores and the HFE 187C>G variant delay onset of peripheral neuropathy during combination antiretroviral therapy
AR Kallianpur, W Wen, AL Erwin, DB Clifford, T Hulgan… - PloS one, 2020 - journals.plos.org
Objective People with HIV (PWH) continue to experience sensory neuropathy and
neuropathic pain in the combination antiretroviral therapy (cART) era for unclear reasons …
neuropathic pain in the combination antiretroviral therapy (cART) era for unclear reasons …
Evaluation of Circulating and Archived HIV-1 Integrase Drug-Resistance Variants among Patients on Third-Line ART in Cameroon: Implications for Dolutegravir …
J Fokam, E Ngoufack Jagni Semengue… - Microbiology …, 2022 - Am Soc Microbiol
To ensure the long-term efficacy of dolutegravir (DTG), we evaluated the genotypic profile in
viral reservoirs among patients on third-line (3L) antiretroviral therapy (ART) in Cameroon …
viral reservoirs among patients on third-line (3L) antiretroviral therapy (ART) in Cameroon …
Evaluation of HIV-1 antiretroviral drug resistance profiles in the peripheral blood reservoir of successfully treated persons using massive sequencing and viral full …
OM Botelho, RP Basso, LD Da Mota… - Journal of …, 2023 - academic.oup.com
Background Antiretroviral therapy has revolutionized HIV treatment, increasing quality and
life expectancy of people living with HIV (PLWH). However, the expansion of treatment has …
life expectancy of people living with HIV (PLWH). However, the expansion of treatment has …