Laboratory biomarkers for diagnosis and prognosis in COVID-19

D Battaglini, M Lopes-Pacheco… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes a wide spectrum of
clinical manifestations, with progression to multiorgan failure in the most severe cases …

Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19

C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in Molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …

Development of novel spectroscopic and machine learning methods for the measurement of periodic changes in COVID-19 antibody level

Z Guleken, YT Tok, P Jakubczyk, W Paja, K Pancerz… - Measurement, 2022 - Elsevier
In this research, blood samples of 47 patients infected by COVID were analyzed. The
samples were taken on the 1st, 3rd and 6th month after the detection of COVID infection …

Saliva metabolomic profile of COVID-19 patients associates with disease severity

N Saheb Sharif-Askari, NC Soares, HA Mohamed… - Metabolomics, 2022 - Springer
Abstract Introduction Coronavirus disease 2019 (COVID-19) is strongly linked to
dysregulation of various molecular, cellular, and physiological processes that change …

Elevation in sphingolipid upon SARS-CoV-2 infection: possible implications for COVID-19 pathology

EB Vitner, R Avraham, B Politi… - Life science …, 2022 - life-science-alliance.org
Understanding pathways that might impact coronavirus disease 2019 (COVID-19)
manifestations and disease outcomes is necessary for better disease management and for …

Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection

J Hou, Y Wei, J Zou, R Jaffery, L Sun, S Liang… - Nature …, 2024 - nature.com
Host anti-viral factors are essential for controlling SARS-CoV-2 infection but remain largely
unknown due to the biases of previous large-scale studies toward pro-viral host factors. To …

Severity of COVID-19 patients predicted by serum sphingolipids signature

E Torretta, M Garziano, M Poliseno… - International Journal of …, 2021 - mdpi.com
The reason behind the high inter-individual variability in response to SARS-CoV-2 infection
and patient's outcome is poorly understood. The present study targets the sphingolipid …

Targeting sphingolipid metabolism as a therapeutic strategy in cancer treatment

AH Janneh, B Ogretmen - Cancers, 2022 - mdpi.com
Simple Summary Sphingolipids, which are important cell membrane components, have
critical roles in regulating cancer cell signaling to control pro-tumoral or antitumoral …

Dynamic modulations of sphingolipids and glycerophospholipids in COVID‐19

M Kurano, K Okamoto, D Jubishi… - Clinical and …, 2022 - Wiley Online Library
Background A heterogeneous clinical phenotype is a characteristic of coronavirus disease
2019 (COVID‐19). Therefore, investigating biomarkers associated with disease severity is …

Altered sphingolipid pathway in SARS-CoV-2 infected human lung tissue

RJ Khan, SL Single, CS Simmons, M Athar… - Frontiers in …, 2023 - frontiersin.org
Introduction The SARS-CoV-2 mediated COVID-19 pandemic has impacted millions
worldwide. Hyper-inflammatory processes, including cytokine storm, contribute to long …