Resistance of gram-negative bacteria to current antibacterial agents and approaches to resolve it

Z Breijyeh, B Jubeh, R Karaman - Molecules, 2020 - mdpi.com
Antimicrobial resistance represents an enormous global health crisis and one of the most
serious threats humans face today. Some bacterial strains have acquired resistance to …

Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health

T Li, Z Wang, J Guo, C de la Fuente-Nunez… - Science of The Total …, 2023 - Elsevier
The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …

[HTML][HTML] Focus: drug development: Penicillin's discovery and antibiotic resistance: lessons for the future?

M Lobanovska, G Pilla - The Yale journal of biology and medicine, 2017 - ncbi.nlm.nih.gov
Undoubtedly, the discovery of penicillin is one of the greatest milestones in modern
medicine. 2016 marks the 75th anniversary of the first systemic administration of penicillin in …

Urinary tract infections: epidemiology, mechanisms of infection and treatment options

AL Flores-Mireles, JN Walker, M Caparon… - Nature reviews …, 2015 - nature.com
Urinary tract infections (UTIs) are a severe public health problem and are caused by a range
of pathogens, but most commonly by Escherichia coli, Klebsiella pneumoniae, Proteus …

Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and cholecystitis

H Gomi, JS Solomkin, D Schlossberg… - Journal of Hepato …, 2018 - Wiley Online Library
Antimicrobial therapy is a mainstay of the management for patients with acute cholangitis
and/or cholecystitis. The Tokyo Guidelines 2018 (TG 18) provides recommendations for the …

The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae

AJ Mathers, G Peirano, JDD Pitout - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Escherichia coli sequence type 131 (ST131) and Klebsiella pneumoniae ST258 emerged in
the 2000s as important human pathogens, have spread extensively throughout the world …

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

S Leclercq, FM Mian, AM Stanisz, LB Bindels… - Nature …, 2017 - nature.com
There is increasing concern about potential long-term effects of antibiotics on children's
health. Epidemiological studies have revealed that early-life antibiotic exposure can …

Extended-spectrum beta-lactamase production and multi-drug resistance among Enterobacteriaceae isolated in Addis Ababa, Ethiopia

DS Teklu, AA Negeri, MH Legese, TL Bedada… - … Resistance & Infection …, 2019 - Springer
Background The global emergence and spread of extended-spectrum beta-lactamases
(ESBLs) producing Enterobacteriaceae have been threatening the ability to treat an …

Genomics of microbial plasmids: classification and identification based on replication and transfer systems and host taxonomy

M Shintani, ZK Sanchez, K Kimbara - Frontiers in microbiology, 2015 - frontiersin.org
Plasmids are important “vehicles” for the communication of genetic information between
bacteria. The exchange of plasmids transmits pathogenically and environmentally relevant …

Antibiotic resistance in pediatric infections: global emerging threats, predicting the near future

A Romandini, A Pani, PA Schenardi, GAC Pattarino… - Antibiotics, 2021 - mdpi.com
Antibiotic resistance is a public health threat of the utmost importance, especially when it
comes to children: according to WHO data, infections caused by multidrug resistant bacteria …