[HTML][HTML] Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Alzheimer's disease and its treatment by different approaches: A review

S Srivastava, R Ahmad, SK Khare - European Journal of Medicinal …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

[HTML][HTML] Nanotechnology-based drug delivery for central nervous system disorders

TT Nguyen, TTD Nguyen, TK Vo, MK Nguyen… - Biomedicine & …, 2021 - Elsevier
Drug delivery to central nervous system (CNS) diseases is very challenging since the
presence of the innate blood–brain barrier (BBB) and the blood-cerebrospinal fluid barrier …

[HTML][HTML] Advances in developing therapeutic strategies for Alzheimer's disease

TT Nguyen, TTD Nguyen, TKO Nguyen, TK Vo - Biomedicine & …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive deterioration of brain function, initially
characterized by cognitive deficits, with loss of recent memory and language ability …

Therapeutic strategies and nano-drug delivery applications in management of ageing Alzheimer's disease

G Karthivashan, P Ganesan, SY Park, JS Kim… - Drug …, 2018 - Taylor & Francis
In recent years, the incidental rate of neurodegenerative disorders has increased
proportionately with the aging population. Alzheimer's disease (AD) is one of the most …

[HTML][HTML] Alzheimer's disease current therapies, novel drug delivery systems and future directions for better disease management

B Singh, CM Day, S Abdella, S Garg - Journal of Controlled Release, 2024 - Elsevier
Abstract Alzheimer's disease (AD), is a neurodegenerative disorder that escalates with time,
exerting a significant impact on physical and mental health and leading to death. The …

New advances in brain-targeting nano-drug delivery systems for Alzheimer's disease

Q Ouyang, Y Meng, W Zhou, J Tong… - Journal of drug …, 2022 - Taylor & Francis
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide and its
incidence is increasing due to the ageing population. Currently, the main limitations of AD …

Multidisciplinary role of mesoporous silica nanoparticles in brain regeneration and cancers: From crossing the blood–brain barrier to treatment

S Mendiratta, M Hussein, HA Nasser… - Particle & Particle …, 2019 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) have gained wide attention for their role in
biomedicine and as drug delivery vehicles. Their structural tunability, high surface area, and …

[HTML][HTML] Nano biomaterials based strategies for enhanced brain targeting in the treatment of neurodegenerative diseases: an up-to-date perspective

DE Nayab, F Din, H Ali, WA Kausar, S Urooj… - Journal of …, 2023 - Springer
Neurons and their connecting axons gradually degenerate in neurodegenerative diseases
(NDs), leading to dysfunctionality of the neuronal cells and eventually their death. Drug …