It has recently been proposed that the intermittent access (IntA) drug self-administration
procedure better produces behavioral changes relevant to addiction than the long access …

The relative value of and motivation for abused drugs often increases with drug experience
and differs based on drug availability. Here, we determined how different intake patterns of …

The intravenous cocaine self-administration model is widely used to characterize the
neurobiology of cocaine seeking. When studies are aimed at understanding relapse to …

The incorporation of microeconomics concepts into studies using self-administration
procedures has provided critical insights into the factors that influence consumption of a …

Environmental cues associated with rewards can acquire motivational properties. However,
there is considerable variation in the extent to which a reward cue gains motivational control …

In humans, reward cues, including drug cues in individuals experiencing addiction, are
especially effective in biasing attention towards them, so much so they can disrupt ongoing …

Rationale Compared to obesity-resistant rats, obesity-prone rats consume more food, work
harder to obtain food, show greater motivational responses to food-cues, and show greater …

In individuals with substance use disorders, stress is a critical determinant of relapse
susceptibility. In some cases, stressors directly trigger cocaine use. In others, stressors …

Model-free and model-based computations are argued to distinctly update action values that
guide decision-making processes. It is not known, however, if these model-free and model …

Pavlovian learning processes can render cues and contexts associated with drug-taking
experiences into powerful motivators, such that exposure to such stimuli can elicit drug …