Precision medicine in gastroenteropancreatic neuroendocrine neoplasms: Where are we in 2023?

N Fazio, A La Salvia - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
Precision medicine describes a target-related approach to tailoring diagnosis and treatment
of the individual patient. While this personalized approach is revoluzionizing many areas of …

PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas

T Cubiella, L Celada… - The Journal of …, 2024 - Wiley Online Library
Neuroendocrine neoplasms (NENs) encompass tumors arising from neuroendocrine cells in
various organs, including the gastrointestinal tract, pancreas, adrenal gland, and …

[HTML][HTML] Advances in understanding and management of high-grade pancreatic neuroendocrine neoplasm: a comprehensive review

DKR Regalla, O Deep, RK Paluri - Chinese Clinical Oncology, 2023 - cco.amegroups.org
High-grade (HG) pancreatic neuroendocrine neoplasms (PAN-NENs) are aggressive and
have a poor prognosis. Yet, our understanding and treatment approaches for these tumors …

[HTML][HTML] Pancreatic Neuroendocrine Tumors: Signaling Pathways and Epigenetic Regulation

Z Saleh, MC Moccia, Z Ladd, U Joneja, Y Li… - International Journal of …, 2024 - mdpi.com
Pancreatic neuroendocrine tumors (PNETs) are characterized by dysregulated signaling
pathways that are crucial for tumor formation and progression. The efficacy of traditional …

Graph Attention Networks for Drug Combination Discovery: Targeting Pancreatic Cancer Genes with RAIN Protocol

E Parichehreh, AA Kiaei, M Boush, D Safaei… - medRxiv, 2024 - medrxiv.org
Background: Malignant neoplasm of the pancreas (MNP), a highly lethal illness with bleak
outlook and few therapeutic avenues, entails numerous cellular transformations. These …

Digital spatial profiling of RNA in pancreatic neuroendocrine tumors highlights the distinct profile of alpha-SMA positive stroma and its impact on surrounding tumor …

H Niedra, R Peculis, R Saksis, S Vilisova, A Breiksa… - bioRxiv, 2023 - biorxiv.org
Objective Alpha smooth muscle actin (alpha-SMA) expression in stroma is linked to the
presence of cancer-associated fibroblasts and is known to correlate with worse outcomes in …

[引用][C] Contemporary Approaches to the Surgical Management of Pancreatic Neuroendocrine Tumors

A Kartik, VL Armstrong, CC Stucky, N Wasif, ZV Fong - Cancers, 2024 - MDPI

[引用][C] Carcinoid Syndrome

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