Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Advances of H2S in Regulating Neurodegenerative Diseases by Preserving Mitochondria Function

L Zhou, Q Wang - Antioxidants, 2023 - mdpi.com
Neurotoxicity is induced by different toxic substances, including environmental chemicals,
drugs, and pathogenic toxins, resulting in oxidative damage and neurodegeneration in …

Hydrogen sulfide plays an important role by regulating endoplasmic reticulum stress in diabetes-related diseases

H Zhao, H Liu, Y Yang, T Lan, H Wang… - International Journal of …, 2022 - mdpi.com
Endoplasmic reticulum (ER) plays important roles in protein synthesis, protein folding and
modification, lipid biosynthesis, calcium storage, and detoxification. ER homeostasis is …

Exogenous hydrogen sulfide alleviates hepatic endoplasmic reticulum stress via SIRT1/FoxO1/PCSK9 pathway in NAFLD

X Cui, M Yao, Y Feng, C Li, Y Li, D Guo… - The FASEB …, 2023 - Wiley Online Library
High‐fat‐induced endoplasmic reticulum (ER) stress has been the main reason for the
occurrence and development of nonalcoholic fatty liver disease (NAFLD). Hydrogen sulfide …

[HTML][HTML] Teneligliptin alleviates diabetes-related cognitive impairment by inhibiting the endoplasmic reticulum (ER) stress and NLRP3 inflammasome in mice

W Wang, J Zhang - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) significantly influences the normal health of patients with its severe
complications, including diabetes-related cognitive impairment (CI). Recently …

Shen Qi Wan ameliorates learning and memory impairment induced by STZ in AD rats through PI3K/AKT pathway

J Huang, Z Xu, H Chen, Y Lin, J Wei, S Wang, H Yu… - Brain Sciences, 2022 - mdpi.com
Alzheimer's disease is the most common form of neurodegenerative disease, and increasing
evidence shows that insulin signaling has crucial roles in AD initiation and progression. In …

Exogenous hydrogen sulfide ameliorates diabetes-associated cognitive dysfunction by regulating the nrf-2/HO-1 axis and the NLRP3 inflammasome pathway in …

H Chen, H Sun, W Hua, H Chang, W Chen… - European Journal of …, 2024 - Elsevier
Diabetes-associated cognitive dysfunction (DACD) is a complication of diabetes mellitus that
leads to an increased risk of cognitive impairment and dementia. However, the molecular …

The Critical Role of Sirt1 in Subarachnoid Hemorrhages: Mechanism and Therapeutic Considerations

Z Zhang, C Liu, X Zhou, X Zhang - Brain Sciences, 2023 - mdpi.com
The subarachnoid hemorrhage (SAH) is an important cause of death and long-term
disability worldwide. As a nicotinamide adenine dinucleotide-dependent deacetylase, silent …