Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

Hydrogel is a three-dimensional network polymer material rich in water. It is widely used in
the biomedical field because of its unique physical and chemical properties and good …

Developing oral nanomedicines that suppress intestinal inflammation while modulating gut
microbiota and brain interactions is essential for effectively treating inflammatory bowel …

Selenoprotein plays a crucial role in immune cells and inflammatory regulation. However, as
a protein drug that is easily denatured or degraded in the acidic environment of the stomach …

Diabetic foot ulcer (DFU) is one of the most common complications of diabetes, bringing
physical and mental challenges for patients due to the lack of efficient curative therapy …

Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Traditional drug-based treatments for inflammatory bowel disease (IBD) have significant
limitations due to their potential off-target systemic side-effects. Currently, there is a lack of …

Abstract Inflammatory Bowel Disease (IBD), a chronic nonspecific intestinal inflammatory
disease, is comprised of Ulcerative Colitis (UC) and Crohn's Disease (CD). IBD is closely …

Introduction High-dose drug administration for the conventional treatment of inflammatory
bowel disease induces cumulative toxicity and serious side effects. Currently, few reports …

Abnormal activation of the gut mucosal immune system and a highly dysregulated gut
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …