The longitudinal pattern of lung function in children with sickle cell anemia (SCA) has shown
a decrease in FEV1% predicted, a risk factor for death in adults with SCA, but predictors for …

Background Asthma and airway hyper-responsiveness are reportedly more common in
children with sickle cell disease (SCD). Aim To determine airway responsiveness, airway …

Lung function in patients with sickle cell anaemia (SCA) living in sub-Saharan Africa is
largely unknown. Anthropometry and spirometry were cross-sectionally evaluated in patients …

Although some of the most severe complications of Sickle Cell Disease (SCD) tend to be
acute and severe (eg acute chest syndrome, stroke etc.), the chronic ones can be equally …

In recent years, evidence has increased that asthma predisposes to complications of sickle
cell disease (SCD), such as pain crises, acute chest syndrome, pulmonary hypertension …

Sickle cell disease (SCD) is an autosomal recessive inherited hematological disorder
characterized by chronic hemolysis and vaso-occlusion, resulting in multiorgan dysfunction …

Hematopoietic cell transplantation (HCT) is an established cure for sickle cell disease (SCD)
supported by long-term survival, but long-term organ function data are lacking. We sought to …

Lung function abnormalities occur in children with sickle cell disease (SCD) and may be
associated with elevated pulmonary blood volume. To investigate that association, we …

Asthma and sickle cell disease (SCD) are common chronic conditions in children of African
ancestry that are characterized by cough, wheeze, and obstructive patterns on pulmonary …

Individuals with sickle cell disease (SCD) develop a decline in lung function over time.
Hydroxyurea (HU) is the most common disease-modifying therapy used in SCD. We …