Background: Stroke has become a major problem around the world, which is one of the
main causes of long-term disability. Therefore, it is important to seek a biomarker to predict …

Stroke remains a significant unmet clinical need with few treatment options that have a very
narrow therapeutic window, thereby causing massive mortality and morbidity in the United …

Microglial activation is considered as the critical pathogenic event in diverse central nervous
system disorders including cerebral ischemia. Proinflammatory responses of activated …

Stroke is a severe and life-threatening disease, necessitating more research on new
treatment strategies. Infiltrated T lymphocytes, an essential adaptive immune cell with …

Atherosclerosis is the major cause of the development of cardiovascular disease, which, in
turn, is one of the leading causes of mortality worldwide. From the point of view of …

Stroke remains one of the most devastating and challenging neurological diseases
worldwide. Inflammation, as well as oxidative stress is one of the main contributors to post …

Although cellular and molecular mediators of the immune system have the potential to be
prognostic indicators of disease outcomes, temporal interference between diseases might …

Aneurysmal subarachnoid hemorrhage (aSAH), with a crude worldwide incidence of around
7.9 per 100,000 person-years [1] and accounting for only 5% of all strokes, is a potentially …

Aims Damage of the blood–brain barrier (BBB) is a hallmark of brain injury during the early
stages of ischemic stroke. The subsequent endothelial hyperpermeability drives the initial …

Although tissue plasminogen activator (t-PA) and endovascular thrombectomy are well-
established treatments for acute ischemic stroke, over half of patients with stroke remain …