In August 2022, these guidelines were reviewed by an expert work group convened by ASH.
Review included limited searches for new evidence and discussion of the search results …

Major pulmonary embolism (PE) results whenever the combination of embolism size and
underlying cardiopulmonary status interact to produce hemodynamic instability. Physical …

Background—Randomized trials and meta-analyses have reached conflicting conclusions
about the role of thrombolytic therapy for the treatment of acute pulmonary embolism …

Background Thrombolytic drugs are widely used for the management of cerebral venous
sinus thrombosis patients. Several in vitro models have been developed to study clot lytic …

Acute massive pulmonary embolism has a high mortality rate. Fatal haemodynamic
deterioration is caused by an acute increase in pulmonary vascular resistance. Traditionally …

Thrombotic disorders have emerged as serious threat to society. As anticoagulant and
thrombolytic therapies are usually associated with serious bleeding complications, the focus …

Background Optimal dosing of the recombinant tissue-type plasminogen activator (rt-PA) is
important in treating pulmonary thromboembolism (PTE). The aim of this study was to …

The prognosis and optimal therapy of patients with pulmonary embolism (PE) are strongly
influenced by the presence or absence of associated hemodynamic derangements. Patients …

Pregnancy due to its physiological changes is a procoagulant state. The rate of cardiac
valve prosthesis thrombosis, deep venous thrombosis and pulmonary embolism are all …

The objective was to evaluate the helical CT (HCT) criteria that could indicate severe
pulmonary embolism (PE). In a retrospective study, 81 patients (mean age 62 years) with …